医学新知2026，Vol.36Issue(3)：329-334,6.DOI:10.12173/j.issn.1004-5511.202510074
层流洁净手术室对腹部手术应用效果的系统评价与Meta分析
The impact of laminar flow clean operating room on abdominal surgery:a systematic review and Meta-analysis
摘要
Abstract
Objective To evaluate the application effect of laminar flow clean operating room and ordinary operating room in abdominal surgery.Method Search CNKI,WanFang,VIP,PubMed,Web of Science,The Cochrane Library and Embase databases to collect clinical studies on the application of laminar flow clean operating rooms and general operating rooms in abdominal surgery.The search period was from the establishment to July 25,2025.Results A total of 9 studies were included,involving 59,449 patients,showing that compared with a regular operating room,laminar flow clean operating rooms significantly reduced the surgical site infection(SSI)incidence[OR=0.50,95%CI(0.34,0.73),P<0.001]and the number of airborne bacteria[MD=-47.32,95%CI(-66.36,-28.29),P<0.001].Subgroup analysis showed that laminar flow clean operating rooms more significantly decreased the SSI incidence in patients<60 years old[OR=0.45,95%CI(0.25,0.83),P=0.01],patients with surgery duration≥150 minutes[OR=0.41,95%CI(0.31,0.55),P<0.001],and patients with a proportion of grade III/IV surgery≥50%[OR=0.41,95%CI(0.21,0.80),P=0.01].The decrease in airborne bacterial counts was more significant in the subgroup with less than 10 door openings during surgery[MD=-65.43,95%CI(-94.47,-36.40),P<0.001].Conclusion Current evidence shows that laminar flow clean operating rooms are more effective in preventing SSI and reducing airborne bacterial count during abdominal surgery than regular operating rooms,especially in specific patient populations and surgical conditions.关键词
层流手术室/腹部手术/手术部位感染/空气菌落数/Meta分析Key words
Laminar flow operating room/Abdominal surgery/Surgical site infection/Airborne bacterial count/Meta-analysis分类
医药卫生引用本文复制引用
付璐,李素英,李小兰,严敏..层流洁净手术室对腹部手术应用效果的系统评价与Meta分析[J].医学新知,2026,36(3):329-334,6.基金项目
成都市医学科研课题(2023181) （2023181）
