中国实验方剂学杂志2026，Vol.32Issue(5)：340-346,7.DOI:10.13422/j.cnki.syfjx.20252164
基于双指数模型的中药吸湿动力学表征及应用研究进展
Characterization and Application of Moisture Absorption Kinetics of Traditional Chinese Medicines Based on Double Exponential Model:A Review
摘要
Abstract
Hygroscopicity research has long been a key focus and hot topic in Chinese materia medica(CMM).Elucidating hygroscopic mechanisms plays a vital role in formulation design,process optimization,and storage condition selection.Hygroscopic models serve as essential tools for characterizing CMM hygroscopic mechanisms,with various types available.The double exponential model is a kinetic mathematical model constructed based on the law of conservation of energy and Fick's first law of diffusion,tailored to the physical properties of CMM extracts.In recent years,this model has been extensively applied to simulate the dynamic moisture absorption behavior of CMM extracts and solid dosage forms under varying humidity conditions.It has revealed the correlation between moisture absorption kinetic parameters and material properties,offering a new perspective for characterizing the moisture uptake behavior of CMM.This paper systematically reviews the application progress of this model in the field of CMM,analyzes its advantages,disadvantages,and challenges in this domain,and explores its potential application trends in other fields.It aims to provide references for elucidating the moisture absorption mechanisms of CMM and researching moisture-proofing technologies,while also offering insights for its broader application in food and polymer materials.关键词
双指数模型/中药/吸湿/动力学模型/提取物/固体制剂Key words
double exponential model/Chinese materia medica/moisture absorption/kinetic models/extracts/solid preparations分类
医药卫生引用本文复制引用
余艳婷,熊磊,何雁,刘微,杨婧,张尧,陈佳莉,罗晓健,饶小勇..基于双指数模型的中药吸湿动力学表征及应用研究进展[J].中国实验方剂学杂志,2026,32(5):340-346,7.基金项目
江西省主要学科和技术带头人培养计划——领军人才项目(20204BCJ22032) （20204BCJ22032）
国家自然科学基金项目(30860382,82060715) （30860382,82060715）
江西省高等学校大学生创新创业训练计划项目(202510412253) （202510412253）
