中国内镜杂志2026，Vol.32Issue(3)：58-64,7.DOI:10.12235/E20250426
注水法圈套器冷切除术在治疗结肠无蒂锯齿状病变中的应用
Application of underwater cold snare polypectomy in the treatment of sessile serrated lesions in the colon
侯思慧 1毕亭亭 1汪晓红 1孟剑秋 2张云霄 3刘益1
作者信息
- 1. 东南大学附属徐州市中心医院 消化内科,江苏 徐州 221000
- 2. 东南大学附属徐州市中心医院 内镜中心,江苏 徐州 221000
- 3. 东南大学附属徐州市中心医院 病理诊断中心,江苏 徐州 221000
- 折叠
摘要
Abstract
Objective To compare the effectiveness and safety of different endoscopic methods for removing colonic sessile serrated lesions(SSL)with a diameter of 6～10 mm by evaluating the rate of complete muscularis mucosae resection and the resection depth of the submucosa tissue.Methods 160 patients with 162 colonic SSL admitted to our hospital from January 2024 to June 2025 were selected as the research subjects.They were randomly divided into cold snare polypectomy(CSP)group,underwater cold snare polypectomy(UCSP)group,underwater endoscopic mucosal resection(UEMR)group,and conventional endoscopic mucosal resection(CEMR)group by random number table.The integrity rate of the mucosal muscular layer,submucosal depth,R0 resection rate,operation time,adverse events and operation cost were compared in four groups.Result The integrity rate of the mucosal muscular layer in the CSP group was significantly lower than that in the other three groups,and the depth of the submucosa was significantly shallower than that in the other three groups.The differences were statistically significant(P<0.05).There was no statistically significant difference in the integrity rate of the mucosal muscular layer among the UCSP group,the UEMR group and the CEMR group(P>0.05).The postoperative pathology of the CEMR group indicated that the depth of the submucosa was the deepest,and there was no statistically significant difference compared with the UEMR group(P>0.05),but it was significantly deeper than that of the UCSP group and CSP group,and the difference was statistically significant(P<0.05).When comparing the depth of the submucosa between the UCSP group and the UEMR group,there was no statistically significant difference(P>0.05).There was no statistically significant difference in the R0 resection rate in the four groups of patients(P>0.05).The operation time of the CEMR group was(187.7±61.5)s,which was significantly longer than that of the other three groups,and the difference was statistically significant(P<0.05).There was no statistically significant difference in the operation time among the other three groups(P>0.05).The surgical costs of the UEMR and CEMR groups was significantly higher than those of the CSP group and the UCSP group,and the difference was statistically significant(P<0.05).No adverse events such as perforation occurred in the four groups of patients.There were no statistically significant differences in transient and delayed bleeding in the four groups of patients(P>0.05).Conclusion Water injection and submucosal injection for the treatment of colon SSL can help increase the resection rate of the muscularis mucosa and achieve deeper submucosal resection.Considering the operation time and cost comprehensively,UCSP is recommended for such lesions,as it is more suitable for promotion in primary hospitals.关键词
圈套器冷切除术(CSP)/注水法圈套器冷切除术(UCSP)/注水法内镜黏膜切除术(UEMR)/传统内镜黏膜切除术(CEMR)/无蒂锯齿状病变(SSL)Key words
cold snare polypectomy(CSP)/underwater cold snare polypectomy(UCSP)/underwater endoscopic mucosal resection(UEMR)/conventional endoscopic mucosal resection(CEMR)/sessile serrated lesions(SSL)分类
医药卫生引用本文复制引用
侯思慧,毕亭亭,汪晓红,孟剑秋,张云霄,刘益..注水法圈套器冷切除术在治疗结肠无蒂锯齿状病变中的应用[J].中国内镜杂志,2026,32(3):58-64,7.
