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影响莫能菌素预混剂溶出度的关键工艺参数研究

徐兴鹏 张凡星 王建丽 赵炳彩 尹宝连 胡言峰

中国奶牛Issue(3):6-9,4.
中国奶牛Issue(3):6-9,4.DOI:10.19305/j.cnki.11-3009/s.2026.03.002

影响莫能菌素预混剂溶出度的关键工艺参数研究

Key Process Parameters Affecting the Dissolution of Monensin Premix

徐兴鹏 1张凡星 1王建丽 1赵炳彩 1尹宝连 1胡言峰1

作者信息

  • 1. 山东胜利生物工程有限公司,济宁 272000
  • 折叠

摘要

Abstract

The effects of the pH value of fermentation broth pretreatment,ratio of corn flour to defatted rice bran,roller pressure,and roller rotation speed on the solubility of monensin premixes in media with different pH values were investigated using orthogonal tests.The results showed that roller pressure and roller rotation speed were identified as the most critical process parameters.The dissolution profiles of the small-and pilot-scale products were all similar to that of the reference listed drug(Elancoban)in the aforementioned media.

关键词

莫能菌素/辊轮压力/辊轮转速/溶出曲线

Key words

Monensin/Roller pressure/Roller rotation speed/The dissolution profiles

分类

农业科技

引用本文复制引用

徐兴鹏,张凡星,王建丽,赵炳彩,尹宝连,胡言峰..影响莫能菌素预混剂溶出度的关键工艺参数研究[J].中国奶牛,2026,(3):6-9,4.

中国奶牛

1004-4264

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