中国全科医学2026,Vol.29Issue(15):1953-1970,18.DOI:10.12114/j.issn.1007-9572.2025.0482
特发性膜性肾病中西医结合诊疗指南(2025)
Diagnosis and Treatment Guideline of Integrated Traditional Chinese and Western Medicine for Idiopathic Membranous Nephropathy(2025)
摘要
Abstract
In China,idiopathic membranous nephropathy(IMN)accounts for 24.9% of glomerular diseases,the second highest share,and is increasing year by year.Combined therapy of Chinese and Western medicine has been widely used in the clinical practice of IMN.However,there are no evidence-based practice guidelines for the treatment of IMN with integrated traditional Chinese and Western medicine.This guideline followed the methods and steps of the guideline development manual.The level of the body of the evidence was assessed by the GRADE.An outline of the clinical questions was formulated through interviews with leading Chinese medicine experts and a review of relevant clinical guidelines.Based on the results of a systematic review of authoritative textbooks and clinical research literature,a clinical question list,a clinical outcome assessment index for IMN,and a list of types of Chinese medicine syndromes were developed,and a national expert survey was conducted to identify the clinical questions included in this guideline.A systematic retrieval of evidence was conducted for the clinical questions included in the guideline,and its quality was assessed.Through an expert consensus meeting,8 recommendations on the integrated traditional Chinese and Western medicine diagnosis and treatment for IMN were finalized.This guideline focuses on the clinical practice of integrated traditional Chinese and Western medicine in the diagnosis and treatment of IMN,and is applicable to healthcare workers who provide Chinese and Western medicine services.关键词
肾小球肾炎,膜性/特发性膜性肾病/中西医结合/中医药疗法/循证实践/诊疗指南Key words
Glomerulonephritis,membranous/Idiopathic membranous nephropathy/Integrated traditional Chinese and Western medicine/Chinese medicine therapy/Evidence-based practice/Diagnosis and treatment guideline分类
医药卫生引用本文复制引用
中华中医药学会肾病分会,广东省中医药学会肾病专业委员会,苏佩玲,杨丽虹,包崑..特发性膜性肾病中西医结合诊疗指南(2025)[J].中国全科医学,2026,29(15):1953-1970,18.基金项目
国家自然科学基金资助项目(82574958) (82574958)
广州市科技局计划项目(2024A03J0117,2024A03J0714,2025A03J3150,2025A03J4062) (2024A03J0117,2024A03J0714,2025A03J3150,2025A03J4062)
省部共建中医湿证国家重点实验室专项(SZ2021ZZ09,SZ2021ZZ36,SZ2024KF11) (SZ2021ZZ09,SZ2021ZZ36,SZ2024KF11)
广东省中医院中医药科学技术研究专项资助项目(YN2023HL03,YN2023MB10,YN2024MS033,YN2024MS019,YN2024G2RPY022) (YN2023HL03,YN2023MB10,YN2024MS033,YN2024MS019,YN2024G2RPY022)