中国中医急症2026，Vol.35Issue(3)：286-290,5.DOI:10.3969/j.issn.1004-745X.2026.03.009
肠杆菌目细菌血流感染中西医临床特点及预后危险因素分析
Enterobacterales Bloodstream Infections:TCM-Western Medicine Clinical Features and Prognostic Risk Factors
摘要
Abstract
Objective:To explore the clinical characteristics of integrated Traditional Chinese and Western Med-icine(TCM-WM)and risk factors for short-term death in patients with Enterobacterales Bloodstream Infection(EB-BSI)in the general intensive care unit(ICU)of a TCM hospital.Methods:Clinical data of patients with EB-BSI admitted to the Department of Critical Care Medicine,Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University from July 2016 to January 2025 were retrospectively analyzed.The TCM-WM clinical characteristics of EB-BSI were summarized.Taking survival status at 28 days after onset as the end-point for prognosis evaluation,binary logistic regression analysis was used to identify independent risk factors for patient death.Results:Patients were aged 53 to 94 years,all with underlying diseases.Patients with syndrome of flaring heat in qifen and yingfen accounted for 60.3%.Compared with the survival group,the death group had more cases of altered mental status,cold extremities,and abnormal bowel sounds(P<0.05),and fewer cases of chills(P<0.05).Compared with other bacterial infections,patients with Klebsiella pneumoniae Bloodstream Infec-tion(KPBSI)had characteristics such as advanced age,higher 28-day mortality,longer time from ICU admission to onset,and higher proportion of Carbapenem-Resistant Enterobacteriaceae(CRE)infection.Multivariate analysis showed that increased SOFA score,altered mental status and deep vein catheterization were independent risk fac-tors for 28-day death in ICU patients with EB-BSI.Conclusion:Most EB-BSI patients in the general ICU of a TCM hospital present with syndrome of flaring heat in qifen and yingfen.KPBSI has a higher mortality rate than other EB-BSI.Altered mental status,deep vein catheterization and increased SOFA scores at the time of EB-BSI occurrence in the ICU are independent risk factors for 28-day death.关键词
血流感染/肠杆菌目细菌/重症监护室/中西医/危险因素Key words
Bloodstream infection/Enterobacterales/Intensive care unit/Integrated traditional Chinese and west-ern medicine/Risk factors分类
医药卫生引用本文复制引用
张鑫,杨思雯,张羽,陈腾飞..肠杆菌目细菌血流感染中西医临床特点及预后危险因素分析[J].中国中医急症,2026,35(3):286-290,5.基金项目
北京市属医院科研培育计划(PZ2023011) （PZ2023011）
