中国实用妇科与产科杂志2026，Vol.42Issue(2)：154-158,5.DOI:10.19538/j.fk2026020107
产前超声检查"软指标"与"硬指标"的临床解读与管理
Clinical interpretation and management of ultrasound"soft indicators"and"hard indicators"in prenatal ultrasound examination
摘要
Abstract
Prenatal ultrasound examination is an important means for screening and evaluating fetal structures.With the improvement in resolution and the accumulation of evidence-based medicine,ultrasound indicators have evolved from empirical identification to refined management tools based on risk stratification."Hard markers"serve as direct evidence of structural malformations and are clear indications for initiating invasive prenatal diagnosis and multidisciplinary treatment."Soft markers",on the other hand,represent minor ultrasound manifestations,and the interpretation of their clinical significance is highly dependent on whether they occur in isolation,the background risk of the mother,and the results of related molecular genetic testing.On entering the era of molecular medicine,with the widespread application of non-invasive prenatal screening,chromosomal microarray technology,and high-throughput sequencing technology,clinicians should understand and master how to construct an integrated diagnosis and treatment model of"image recognition-risk stratification-molecular diagnosis-prognosis assessment-individualized counseling",and learn how to move from static image recognition to evidence-based quantification and from abnormal static records to systematic pathological reasoning.关键词
产前超声/软指标/硬指标/遗传学检测/风险分层管理Key words
prenatal ultrasound/soft markers/hard makers/genetic testing/risk stratification management分类
医药卫生引用本文复制引用
梁爽,常颖..产前超声检查"软指标"与"硬指标"的临床解读与管理[J].中国实用妇科与产科杂志,2026,42(2):154-158,5.基金项目
国家自然科学基金面上项目(82571979) （82571979）
天津市工健委高层次人才项目(TJWJ2024RC017) National Natural Science Foundation of China—General Program(82571949) （TJWJ2024RC017）
High-level Talent Program of Tianjin Municipal Health Commission(TJWJ2024RC017) （TJWJ2024RC017）
