中国药业2026，Vol.35Issue(7)：48-54,7.DOI:10.3969/j.issn.1006-4931.2026.07.009
基于数据挖掘的不同证型便秘治疗方药味配伍共性特点研究
Common Characteristics of the Compatibility of Medicinal Flavors in the Treatment Formulas for Constipation with Different Syndromes Types Based on Data Mining
摘要
Abstract
Objective To investigate the common characteristics of the compatibility of medicinal flavors in the treatment formulas for constipation with different syndromes types,and provide ideas for selecting medicinal flavors for clinical treatment of constipation.Methods Chinese herbal prescriptions and Chinese patent prescriptions in the treatment of constipation in the traditional Chinese medicine(TCM)clinical expert consensus,systematic review and clinical experience prescriptions were collected to clarify their compatibility structure and efficacy characteristics,the distribution of medicinal flavors was statistically analyzed,and the hierarchical cluster analysis was carry out.Compared with the pungent(harmonization flavor),salty(purgation flavor),sour(tonification flavor)and bitter sweet synthesize salty in the treatment of lung diseases in the Tang-Ye-Jing-Fa Map,the proportion of medicinal flavors was calculated,and the characteristics of the representative prescriptions was analyzed.Results A total of 34 Chinese herbal prescriptions and Chinese patent prescriptions in the treatment of constipation were retrieved,including modified Jichuan Decoction,modified Maziren Pills,modified Wenpi Decoction,Simo Decoction Oral Liquid,Tongbianling Capsules,etc.After excluding the combination of bitter sweet synthesize salty,among the 34 prescriptions,salty sour and pungent herbs account for a proportion above 80%in 25 prescriptions,six prescriptions account for a proportion of 60%-80%,and three prescription accounts for a proportion below 60%;bitter and sweet herbs were mainly concentrated in the lung and spleen or lung and kidney prescriptions.Three clusters were obtained by the hierarchical cluster analysis,and the dominant herb flavor was salty.Conclusion The prescriptions for the treatment of constipation mainly focus on treating the lung,with salty sour and pungent as its core medicinal flavors,salty as its dominant medicinal flavor,and bitter or sweet flavor often used for the co-treatment of mother-to-child diseases,such as the co-treatment of lung and spleen or lung and kidney.关键词
汤液经法图/辅行诀/便秘/中药方/中成药方/药味配伍特点Key words
Tang-Ye-Jing-Fa Map/Fuxingjue/constipation/Chinese herbal prescriptions/Chinese patent prescriptions/compatibility characteristics of medicinal flavors分类
医药卫生引用本文复制引用
赵依佳,郭红叶,齐明月,金锐..基于数据挖掘的不同证型便秘治疗方药味配伍共性特点研究[J].中国药业,2026,35(7):48-54,7.基金项目
全国中药特色技术传承人才培训项目[国中医药人教函[2023]96号] （）
中国中医科学院西苑医院能力提升项目[XYZX0202-07] （）
中国中医科学院科技创新工程重大攻关项目[CI2021A03805]. （）
