中国医学工程2026，Vol.34Issue(2)：21-26,6.DOI:10.19338/j.issn.1672-2019.2026.02.005
颈动脉内膜剥脱术局部脑氧饱和度与术后脑血管反应性、神经认知功能的关系探讨
Exploring the relationship between intraoperative local cerebral oxygen saturation and postoperative cerebral vascular reactivity and neurocognitive function in carotid endarterectomy
韩万里 1胡灵 1杜艳姣 2王会林 2温志国2
作者信息
- 1. 郑州大学附属洛阳中心医院 血管外科,河南 洛阳 471000
- 2. 郑州大学附属洛阳中心医院 神经内科,河南 洛阳 471000
- 折叠
摘要
Abstract
[Objective]To explore the relationship between intraoperative local cerebral oxygen saturation and postoperative cerebral vascular reactivity and neurocognitive function in carotid endarterectomy.[Methods]A total of 141 patients who underwent carotid endarterectomy in Luoyang Central Hospital Affiliated to Zhengzhou University from February 2020 to September 2024 were selected for the study,and the intraoperative local cerebral oxygen saturation and postoperative cerebral vascular reactivity of the patients were detected,and the patients were divided into a cognitive normal group(n=97)and a cognitive impairment group(n=44)according to the Montreal Cognitive Assessment(MoCA)scale scores.The intraoperative local cerebral oxygen saturation,postoperative cerebral vascular reactivity,MoCA scale scores and general information were compared between the two groups.The relationship between intraoperative local cerebral oxygen saturation and postoperative cerebral vascular reactivity and neurocognitive function were analyzed according to the Pearson's method,and the relevant factors affecting cognitive function after carotid endarterectomy were analyzed by logistic regression.[Results]Forty-four cases showed cognitive dysfunction among 141 patients after carotid endarterectomy,and the incidence rate was 31.21%.The proportion of patients with age≥65 years and diabetes in the cognitive dysfunction group were higher(P＜0.05),and the intraoperative local cerebral oxygen saturation,postoperative cerebral vascular reactivity and MoCA scale score were lower(P＜0.05).Pearson correlation analysis showed that intraoperative local cerebral oxygen saturation was positively correlated with postoperative cerebral vascular reactivity and neurocognitive function(P＜0.05),and the postoperative cerebral vascular reactivity was also positively correlated with neurocognitive function(P＜0.05).Logistic regression analysis showed that age,diabetes,intraoperative local cerebral oxygen saturation and postoperative cerebrovascular reactivity were the influencing factors of cognitive dysfunction after carotid endarterectomy(P＜0.05).[Conclusion]There are correlations between intraoperative local cerebral oxygen saturation and postoperative cerebral vascular reactivity and neurocognitive function in carotid endarterectomy,and there is also a correlation between postoperative cerebral vascular reactivity and neurocognitive function,and the intraoperative local cerebral oxygen saturation and postoperative cerebral vascular reactivity are both influencing factors of cognitive dysfunction after carotid endarterectomy.关键词
颈动脉内膜剥脱术/脑血管反应性/局部脑氧饱和度/认知功能/相关性Key words
carotid endarterectomy/cerebral vascular reactivity/local cerebral oxygen saturation/cognitive function/correlation分类
医药卫生引用本文复制引用
韩万里,胡灵,杜艳姣,王会林,温志国..颈动脉内膜剥脱术局部脑氧饱和度与术后脑血管反应性、神经认知功能的关系探讨[J].中国医学工程,2026,34(2):21-26,6.
