中国畜禽种业2026，Vol.22Issue(3)：15-27,13.
单细胞测序在畜禽上的应用
Application of single-cell sequencing in livestock and poultry
摘要
Abstract
Traditional population-level sequencing struggles to resolve cellular heterogeneity,hindering precise research and breeding in the livestock and poultry sector.Single-cell sequencing has developed into genomic,transcriptomic,and epigenomic sequencing technologies.This paper systematically outlines its core principles and processes,focusing on its applications in livestock and poultry reproduction,development,immunology,nutritional metabolism,etc.,and analyzes its practices in the genetic breeding of cattle,pigs,poultry,etc.Its core value lies in breaking the population average effect,accurately capturing cellular heterogeneity and developmental dynamics,deciphering the molecular mechanisms of economic traits such as meat quality and lactation,and screening key genetic markers.Currently,it has achieved remarkable results in optimizing cattle lactation,improving pork quality,enhancing poultry egg-laying performance,and disease prevention and control.关键词
单细胞测序/畜禽育种/细胞异质性/多模态分析/空间转录组学Key words
Single-cell sequencing/Livestock and poultry breeding/Cellular heterogeneity/Multimodal analysis/Spatial transcriptomics分类
农业科技引用本文复制引用
张冰,高明,张灵霜,史丽莎,殷宗俊,郑先瑞..单细胞测序在畜禽上的应用[J].中国畜禽种业,2026,22(3):15-27,13.基金项目
安徽省高校协同创新项目(GXXT-2023-059) （GXXT-2023-059）
安徽省高等学校科学研究重大项目(2024AH040083) （2024AH040083）
国家自然科学基金项目(32102510). （32102510）
