中国畜禽种业2026，Vol.22Issue(3)：51-55,5.
m6A在反刍动物繁殖方面的研究进展
Research progress of m6A in ruminant reproduction
摘要
Abstract
N6-methyladenosine(m6A),the most prevalent epigenetic modification in eukaryotic RNA,plays a critical role in post-transcriptional regulation by modulating RNA splicing,translation,and stability,thereby influencing key biological processes such as the cell cycle and developmental fate.In recent years,research on m6A modification in the context of animal reproduction has advanced significantly,particularly in elucidating its essential functions during oocyte maturation and spermatogenesis.Studies have demonstrated that m6A precisely regulates the expression of reproduction-related genes through the coordinated activity of methyltransferases,demethylases,and binding proteins.Furthermore,m6A contributes to reproductive efficiency by mediating pathways such as placental development and seasonal estrus.This review summarizes the molecular mechanisms underlying m6A-mediated regulation and highlights recent advances in understanding its role in ruminant reproduction.关键词
m6A修饰/表观遗传/动物繁殖Key words
m6A modification/Epigenetics/Animal reproduction分类
农业科技引用本文复制引用
刘奥兵,王二耀,于翔,张子敬,王香南,鲁立刚,刘贤,祁兴山,院鹏,闫祥洲..m6A在反刍动物繁殖方面的研究进展[J].中国畜禽种业,2026,22(3):51-55,5.基金项目
国家肉牛牦牛产业技术体系(CARS-37) （CARS-37）
河南省肉牛产业技术体系项目(HARS-22-13-S) （HARS-22-13-S）
河南省科技攻关(252102110073) （252102110073）
河南省自然基金项目(252300420687) （252300420687）
河南省农业科学院自主创新项目(2025ZC66,2025ZC67) （2025ZC66,2025ZC67）
河南省农业科学院科技创新团队项目牛羊繁育与生产(2024TD25) （2024TD25）
河南省牛产业科技特派员服务团(泌阳) （泌阳）
神农种业实验室协同创新项目(SN02-2025-02). （SN02-2025-02）
