中国畜禽种业2026，Vol.22Issue(3)：82-92,11.
不同猪种重要经济性状的SNP分型研究
SNP typing studies on economically important traits in different outbred pigs
摘要
Abstract
This study aimed to analyze the genotyping of functional gene mutation sites associated with important economic traits in threedifferent exotic pig breeds.Utilizing the"Zhongxin-1"chip,single nucleotide polymorphism analysis was performed on a total of 50 healthy breeding pigs,including 9 Duroc,12 Landrace,and 29 Yorkshire pigs.Following quality control of the SNP genotypic data,genotyping and statistical analysis were conducted for 18 important economic trait-related SNP loci across the different breeds.After quality control of SNP genotype data,18 target genes related to important economic traits such as feed intake,feed-to-meat ratio,and semen quality were selected,and SNP loci of these target genes were genotyped and statistically analyzed.The analysis revealed the frequency distribution of superior genotypes(Q,favorable allele)and non-superior genotypes(q,unfavorable allele)across the different pig breeds.For example,the proportion of QQ genotype for the sour meat gene and semen quality gene in Landrace pigs reaches 100％,which is significantly higher than that in Duroc pigs(sour meat gene 66.67％,semen quality gene 33.33％).The main results indicated that several deleterious alleles(q)have been effectively eliminated from the core population.For instance,the frequency of the QQ genotype reached 100％for the severe combined immunodeficiency gene,hypercholesterolemia gene,hereditary hemorrhagic disease gene,and microtia gene,thereby improving the overall health status of the population.Secondly,the body length gene and dwarfism gene exhibited 100％homozygous non-superior(qq)genotypes across all breeds,indicating the loss of their favorable alleles(Q)within the population.Alternative associated loci could be sought for genetic improvement in these traits.Furthermore,the study identified significant differences(P＜0.05)in the frequencies of the RN gene,semen quality-related genes,and the increased rib number gene among the Duroc,Landrace,and Yorkshire populations using the chi-square test.This study systematically analyzed the genotype distributions of genes associated with key economic traits in the core population,generating data on allele frequencies(favorable vs.unfavorable),homozygosity status,and inter-population differences across breeds.关键词
杜洛克猪/长白猪/大白猪/单核苷酸多态性/重要经济性状/基因频率Key words
Duroc pig/Landrace pig/Yorkshire pig/Single nucleotide polymorphism/Important economic traits/Gene frequency分类
农业科技引用本文复制引用
蔡煜楷,王卓玛才让,薛云,罗淦,梁艳,陶璇,康润敏,顾以韧,刘鹏亮..不同猪种重要经济性状的SNP分型研究[J].中国畜禽种业,2026,22(3):82-92,11.基金项目
四川省科技计划项目(2024YFHZ0373) （2024YFHZ0373）
西藏自治区科技计划项目(32472888) （32472888）
四川省生猪创新团队项目(sccxtd-2025-08). （sccxtd-2025-08）
