摘要
Abstract
Objective To investigate the clinical characteristics of elderly sepsis and establish a mortality risk as-sessment scale suitable for elderly sepsis patients.Methods A retrospective analysis was conducted on the clinical data of 100 elderly sepsis patients admitted to the Department of Critical Care Medicine,Fujian Provincial Geriatric Hospital from December 2022 to December 2024.Based on the 28-day outcome,patients were divided into a survival group(66 cases)and a death group(34 cases).Demographic data,underlying diseases,clinical features,laboratory indicators,and treatment measures were compared between the two groups.Independent risk factors for death in elderly sepsis patients were screened.A mortality risk assessment scale for elderly sepsis patients(SSDRS)was constructed,and its predictive value was evaluated using ROC curves.Results Univariate analysis showed significant differences between the death group and the survival group in terms of age,comorbid chronic renal insufficiency,initial SOFA score,initial APACHE Ⅱ score,Scr,PCT,APTT,FIB,Lac,duration of antibiotic use,duration of mechanical ventilation,and rate of continuous renal replacement therapy(P<0.05).Multivariate logistic regression analysis indicated that age,comorbid chronic renal insuffi-ciency,initial SOFA score,initial APACHE Ⅱ score,Scr,PCT,APTT,Lac,mechanical ventilation,and continuous renal re-placement therapy were independent risk factors for death in elderly sepsis patients.The AUC of the SSDRS scale was sig-nificantly higher than that of the APACHE Ⅱ scale and the SOFA scale(Z=2.891,P=0.004).Conclusion Age,comorbid chronic renal insufficiency,initial SOFA score,initial APACHE Ⅱ score,Scr,PCT,APTT,Lac,mechanical ventilation,and continuous renal replacement therapy are independent risk factors for death in elderly sepsis patients.The SSDRS scale,established based on the above risk factors,can provide a basis for the formulation of clinical treatment strategies.关键词
老年/脓毒症/死亡风险Key words
elderly/sepsis/mortality risk
