中国中医骨伤科杂志2026，Vol.34Issue(4)：54-59,6.DOI:10.20085/j.cnki.issn1005-0205.260409
改良髓芯减压术联合骨形态发生蛋白活性诱导棒植入术治疗早期股骨头缺血性坏死的临床观察
Clinical Observation of Improved Porous Core Decompression Combined with Bone Morphogenetic Protein-Activated Inducing Rod Implantation for the Treatment of Early Ischemic Necrosis of the Femoral Head
摘要
Abstract
Objective:To observe the clinical efficacy of early-stage avascular necrosis of the femoral head(ANFH)using modified porous core decompression combined with implantation of a bone morphogenetic protein-activating rod.Methods:From May 2022 to June 2024,80 patients with early ANFH who received medical treatment were grouped into the decom-pression group(40 cases,adopted improved porous core decompression)and the joint group(40 cases,adopted improved porous core decompression+bone morphogenetic protein activity induction rod implantation)complying with the treat-ment method.Two groups were compared in terms of postoperative clinical efficacy,perioperative indicators,pain visual analogue scale(VAS)score,Harris hip score,bone metabolism markers,and postoperative complications.Results:After surgery,the joint group had an excellent or good rate of 92.50%(37/40),which was significantly higher than that of the decompression group 75.00%(30/40)(P<0.05).Both groups showed a decrease in VAS scores after surgery,with the joint group exhibiting significantly lower scores than the decompression group(P<0.05).Both groups had clearly increased Harris score((86.32±18.38)points vs(78.14±15.25)points),osteocalcin(OC),and bone morphogenetic protein-2(BMP-2)after surgery,with the joint group being clearly higher than the decompression group(P<0.05).For the joint group,the decompression group had significantly shorter surgical time((62.12±7.10)min vs(52.12±6.20)min)and less intraoperative bleeding((132.10±15.60)mL vs(102.31±12.30)mL)(P<0.05).The postoperative complications were not clearly different between two groups(P>0.05).Conclusion:The joint use of improved porous core decompression with bone morphogenetic protein activity in-duction rod implantation for ANFH can improve the excellent rate of patients.It can reduce VAS score,improve Harris hip score and bone metabolism,and has high safety.关键词
改良髓芯减压术/骨形成蛋白活性诱导棒植入术/早期股骨头缺血性坏死Key words
improved porous-core decompression surgery/bone morphogenetic protein-inducing rod implantation surg-ery/early-stage avascular necrosis of the femoral head分类
医药卫生引用本文复制引用
谢志涛,乔国勇,陈欣志,张永涛,田再杰,马智林,王珅,刘博宇,何全杰,褚兆珍..改良髓芯减压术联合骨形态发生蛋白活性诱导棒植入术治疗早期股骨头缺血性坏死的临床观察[J].中国中医骨伤科杂志,2026,34(4):54-59,6.基金项目
河北省卫生健康委员会资助项目(20220656) （20220656）
