安徽中医药大学学报2026，Vol.45Issue(2)：58-64,7.DOI:10.3969/j.issn.2095-7246.2026.02.012
火针围刺联合复方泽漆冲剂治疗斑块型银屑病临床观察
Clinical Effect of Fire Needle Surrounding Acupuncture Combined with Compound Zeqi Granule in Treatment of Plaque Psoriasis
摘要
Abstract
Objective To investigate the clinical effect of fire needle surrounding acupuncture combined with Compound Zeqi Granule in the treatment of plaque psoriasis,as well as dermoscopic changes.Methods A total of 66 patients with plaque psoriasis with blood heat syn-drome were divided into observation group and control group using a random number table,with 33 patients in each group.The patients in the control group were given placebo acupuncture combined with oral administration of Compound Zeqi Granule,and those in the observa-tion group were given fire needle surrounding acupuncture combined with oral administration of Compound Zeqi Granule.Both groups were treated for 8 consecutive weeks,and the two groups were compared in terms of Psoriasis Area and Severity Index(PASI)score,the change in the number of vascular globules under dermoscopy,blood heat syndrome score,Dermatology Life Quality Index(DLQI)score,and Hamilton Anxiety Rating Scale(HAMA)score before treatment and at weeks 2,4,6,and 8 of treatment,as well as clinical outcomes and adverse reaction.Compared PASI50/PASI75/PASI90 response rates of both groups at 2,4,6 and 8 of treatment.Results At weeks 4,6,and 8 of treatment,both groups had significant reductions in PASI score,blood heat syndrome score,and the number of vascular globules(P＜0.05),and the observation group had significantly greater reductions than the control group(P＜0.05).At weeks 4 and 6 of treatment,the observation group had a significantly higher PASI50 response rate than the control group(P＜0.05),and at week 8 of treatment,the observation group had significantly higher PASI50 and PASI75 response rates than the control group(P＜0.05).At weeks 6 and 8 of treatment,both groups had significant reductions in DLQI and HAMA scores,and the observation group had significantly greater reductions than the control group(P＜0.05).The observation group had a significantly better clinical outcome than the control group(P＜0.05).There were no serious adverse events in ei-ther group during treatment.Conclusion Fire needle surrounding acupuncture combined with Compound Zeqi Granule has a marked effect in the treatment of plaque psoriasis and can improve blood heat syndrome,enhance quality of life,alleviate anx-ious emotions,and reduce the number of vascular globules under dermoscopy.关键词
火针围刺/复方泽漆冲剂/斑块型银屑病/血热证/皮肤镜Key words
Fire needle surrounding acupuncture/Compound Zeqi Granule/Plaque psoriasis/Blood heat syndrome/Dermoscopy分类
医药卫生引用本文复制引用
许冉,王佳佳,彭家丰,张振丰,杨心茹,桂浩宇,丁宁,王艳,吴敏..火针围刺联合复方泽漆冲剂治疗斑块型银屑病临床观察[J].安徽中医药大学学报,2026,45(2):58-64,7.基金项目
安徽省高等学校科学研究项目(2024AH051042) （2024AH051042）
