高等学校化学学报2026，Vol.47Issue(4)：72-84,13.DOI:10.7503/cjcu20260002
近红外激发有机发光材料的构筑及在疾病治疗中的应用
Construction of Near-infrared Triggered Organic Photosensitive Materials and Their Applications in Disease Treatment
摘要
Abstract
Phototherapy,mainly including photodynamic therapy(PDT)and photothermal therapy(PTT),has emerged as a promising non-invasive alternative due to its precision and minimal side effects.Compared with inorganic photosensitive materials,organic photosensitive materials offer advantages in terms of biocompatibility,structural tunability and precise structural purity.However,most clinically approved photosensitizers require activation by visible light(400-700 nm)and the limited tissue penetration depth severely restricts their therapeutic efficacy.In contrast,near-infrared light(NIR,700-2500 nm)exhibits superior tissue penetration capacity and causes less damage to healthy tissues,making the optimal optical window for biomedical applications.Therefore,the development of high-performance NIR-absorbing organic photosensitive materials is significance.This article syste-matically reviews the molecular design,performance optimization,and biological application strategies of near-infrared organic photosensitive materials,providing a forward-looking perspective for the construction of a new generation of integrated diagnosis and treatment phototherapy platform.关键词
有机发光材料/聚集诱导发光材料/近红外光Key words
Organic luminescent material/Aggregation-induced emission material/Near-infrared light分类
化学化工引用本文复制引用
孙妍,朱东霞..近红外激发有机发光材料的构筑及在疾病治疗中的应用[J].高等学校化学学报,2026,47(4):72-84,13.基金项目
国家自然科学基金(批准号:52473167)、吉林省重点科技项目(批准号:20240402036GH)和吉林省发展和改革委员会项目(批准号:2024C017-4)资助. Supported by the National Natural Science Foundation of China(No.52473167),the Key Scientific and Technological Project of Jilin Province,China(No.20240402036GH)and the Program of Development and Reform Commission of Jilin Province,China(No.2024C017-4). （批准号:52473167）
