中国实用神经疾病杂志2026，Vol.29Issue(3)：390-396,7.DOI:10.12083/SYSJ.251145
血运重建术治疗大面积脑梗死的研究进展
Research advances in revascularization surgery for the treatment of massive cerebral infarction
摘要
Abstract
Massive cerebral infarction(MCI),a critical neurosurgical challenge,refers to extensive ischemic necrosis of brain tissue caused by occlusion of the main trunk of the middle cerebral artery or internal carotid artery.The international academic community has yet to establish unified diagnostic criteria for this condition,which accounts for approximately 10%of ischemic stroke cases and is characterized by high rates of disability and mortality.In recent years,cerebral revascularization techniques have demonstrated significant therapeutic advantages in reducing transient ischemic attack(TIA)incidence,stroke recurrence risk,and stroke-related mortality through improved cerebral perfusion in ischemic regions and activation of penumbral neuronal function.This review systematically examines research advancements in revascularization strategies for MCI,with particular emphasis on the clinical applications of direct revascularization(superficial temporal artery-middle cerebral artery anastomosis,STA-MCA),indirect revascularization(encephalo-duro-arterio-synangiosis,EDAS),and combined surgical approaches.关键词
大面积脑梗死/联合血运重建术/直接血运重建术/间接血运重建术/干细胞移植/基因治疗Key words
Massive cerebral infarction/Combined revascularization/Direct revascularization/Indirect revascularization/Stem cell transplantation/Gene therapy分类
医药卫生引用本文复制引用
项勇,吴跃辉,向欣..血运重建术治疗大面积脑梗死的研究进展[J].中国实用神经疾病杂志,2026,29(3):390-396,7.基金项目
2023年医疗服务与保障能力提升(医疗卫生机构能力建设)中央补助资金项目(编号:国家临床重点专科-神经外科,2023-95) （医疗卫生机构能力建设）
第二十七届中国科协年会系列学术活动项目(编号:2025XSJL018) （编号:2025XSJL018）
贵州医科大学附属医院院级课题(编号:gyfynsfc[2023]-29) （编号:gyfynsfc[2023]-29）
