基因与疾病（英文）2026，Vol.13Issue(1)：323-334,12.DOI:10.1016/j.gendis.2025.101634
Advancing cancer research:Cutting-edge insights from colorectal cancer patient-derived xenograft mouse models
Advancing cancer research:Cutting-edge insights from colorectal cancer patient-derived xenograft mouse models
Yalan Lu 1Xiaokang Lei 2Yanfeng Xu 1Yanhong Li 1Ruolin Wang 1Siyuan Wang 1Aiwen Wu 3Chuan Qin4
作者信息
- 1. NHC Key Laboratory of Human Disease Comparative Medicine,Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases,International Center for Technology and Innovation of Animal Model,Institute of Laboratory Animal Sciences,Chinese Academy of Medical Sciences(CAMS)& Comparative Medicine Center,Peking Union Medical College(PUMC),Beijing 100021,China
- 2. Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing),Name of Department of Unit Ⅲ & Ostomy Service,Gastrointestinal Cancer Center,Peking University Cancer Hospital & Institute,Beijing 100142,China
- 3. State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers,Beijing Key Laboratory of Carcinogenesis and Translational Research,Department of Unit Ⅲ & Ostomy Service,Gastrointestinal Cancer Center,Peking University Cancer Hospital & Institute,Beijing 100142,China
- 4. NHC Key Laboratory of Human Disease Comparative Medicine,Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases,International Center for Technology and Innovation of Animal Model,Institute of Laboratory Animal Sciences,Chinese Academy of Medical Sciences(CAMS)& Comparative Medicine Center,Peking Union Medical College(PUMC),Beijing 100021,China||Changping National Laboratory(CPNL),Beijing 102200,China
- 折叠
摘要
关键词
Colorectal cancer/Drug screening/Patient-derived xenograftmodel/Precision medicine/Preclinical trial/Resistance/Translational research/Tumor evolutionKey words
Colorectal cancer/Drug screening/Patient-derived xenograftmodel/Precision medicine/Preclinical trial/Resistance/Translational research/Tumor evolution引用本文复制引用
Yalan Lu,Xiaokang Lei,Yanfeng Xu,Yanhong Li,Ruolin Wang,Siyuan Wang,Aiwen Wu,Chuan Qin..Advancing cancer research:Cutting-edge insights from colorectal cancer patient-derived xenograft mouse models[J].基因与疾病（英文）,2026,13(1):323-334,12.基金项目
This work was supported by the National Natural Science Foundation of China(No.82303782),Beijing Natural Sci-ence Foundation(No.7252096),the Young Elite Scientists Sponsorship Program by CAST(No.2022QNRC001),and the Non-Profit Central Research Institute Fund of the Chinese Academy of Medical Sciences(No.2023-PT180-01). （No.82303782）
