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Targeting Wnt/β-catenin activation in combination with temozolomide leads to glioblastoma inhibition and long-term survival in mice

Xiaowei Zhang Zhongyong Wang Taohui Ouyang Brayden Wang Richard I.Joh Suyun Huang

基因与疾病（英文）2026，Vol.13Issue(1)：492-505,14.

基因与疾病（英文）2026，Vol.13Issue(1)：492-505,14.DOI:10.1016/j.gendis.2025.101624

Targeting Wnt/β-catenin activation in combination with temozolomide leads to glioblastoma inhibition and long-term survival in mice

Xiaowei Zhang ¹Zhongyong Wang ²Taohui Ouyang ¹Brayden Wang ³Richard I.Joh ⁴Suyun Huang¹

作者信息

1. Department of Human and Molecular Genetics,School of Medicine,Virginia Commonwealth University,Richmond,VA 23298,USA||Massey Cancer Center,Virginia Commonwealth University,Richmond,VA 23298,USA
2. Department of Neurosurgery,The University of Texas MD Anderson Cancer Center,Houston,TX 77030,USA
3. Department of Pharmacology and Toxicology,Virginia Commonwealth University,Richmond,VA 23298,USA
4. Massey Cancer Center,Virginia Commonwealth University,Richmond,VA 23298,USA||Department of Physics,Virginia Commonwealth University,Richmond,VA 23219,USA
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摘要

关键词

Chemoresistance/Glioblastoma/Temozolomide/Wnt inhibitor/Wnt/β-catenin

Key words

Chemoresistance/Glioblastoma/Temozolomide/Wnt inhibitor/Wnt/β-catenin

引用本文复制引用

Xiaowei Zhang,Zhongyong Wang,Taohui Ouyang,Brayden Wang,Richard I.Joh,Suyun Huang..Targeting Wnt/β-catenin activation in combination with temozolomide leads to glioblastoma inhibition and long-term survival in mice[J].基因与疾病（英文）,2026,13(1):492-505,14.

基金项目

This work was supported in part by Paul M.Corman,MD Chair in Cancer Research Endowment Fund. （）

基因与疾病（英文）

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