农药学学报2026，Vol.28Issue(2)：197-215,19.DOI:10.16801/j.issn.1008-7303.2026.0029
新烟碱类农药在植物系统中的迁移转化行为及生物学效应研究进展
Research progress on translocation,transformation,and biological effects of neonicotinoid pesticides in plant systems
摘要
Abstract
The extensive use of neonicotinoid pesticides has resulted in their residual accumulation in various environmental media,including soil,water,and atmospheric deposition.This poses a threat to organisms at multiple levels.These compounds can be absorbed,accumulated,and metabolically transformed by plants,thereby compromising crop quality and the safety of agricultural products.This class of pesticides exhibits strong systemic properties:after absorption,they can be translocated within plants,with tissue distribution being co-determined by the physicochemical properties of the pesticides and the crop species.Once taken up,neonicotinoids undergo multi-phase metabolism mediated by enzyme systems such as cytochrome P450 monooxygenases and glutathione S-transferases.The biological effects of neonicotinoid pesticides are both dose-and crop-specific.Excessive concentrations can interfere with normal plant physiology functions,inhibit nutrient absorption,and impair quality formation.Various phytohormone signaling pathways play a critical roles in plant responses to neonicotinoid pesticide stress,which can effectively alleviate plant stress effects and reduce pesticide residue accumulation by regulating the antioxidant systems and metabolic detoxification networks.This review systematically summarizes recent research progress on neonicotinoid pesticides in terms of their environmental occurrence and toxicity risks,absorption,translocation,and metabolic transformation in plants,effects on plant growth,development,and quality,as well as the molecular mechanisms underlying hormone-regulated detoxification and residue reduction.We further highlight key scientific questions that warrant in-depth investigation,including the molecular mechanisms of multi-phase metabolism,metabolic residue characteristics,the regulatory networks of plant responses to pesticide stress-particularly the roles of key signaling receptors and the transcriptional regulation of detoxification genes,aiming to provide a reference for future research on crop germplasm innovation and residue pollution strategies.关键词
新烟碱类农药/代谢转化/植物效应/调控网络/基因转录/植物源调节剂Key words
neonicotinoid pesticides/metabolic transformation/plant effects/regulatory networks/gene transcription/plant-derived regulators分类
资源环境引用本文复制引用
范雯雯,肖灿,刘海军,陈浪,查成敏,周利,王新茹..新烟碱类农药在植物系统中的迁移转化行为及生物学效应研究进展[J].农药学学报,2026,28(2):197-215,19.基金项目
国家重点研发计划(No.2022YFD1600803). Supported by National Key Research and Development Program of China(No.2022YFD1600803). （No.2022YFD1600803）
