生物医学工程研究2026，Vol.45Issue(1)：7-14,8.DOI:10.19529/j.cnki.1672-6278.2026.01.02
电阻抗断层成像与脑电同步检测系统研发及其在癫痫病灶定位中的可行性研究
Development of an EIT-EEG synchronous detection system and feasibility study for epileptic zone localization
摘要
Abstract
Regarding the problem for precise localization of refractory epileptic nidus,we developed an electrical impedance tomo-graphy(EIT)and electroencephalogram(EEG)synchronous detection system to verify the feasibility and accuracy of EIT in the localiza-tion of epileptogenic zone(EZ).The system employed the same set of electrodes to achieve simultaneous,synchronous and co-channel acquisition of impedance and EEG signals.The dual-domain collaborative strategy of"hardware low-pass+software comb"was used to eliminate mutual interference between devices,and ensure the accuracy of signal acquisition.The test results on 20 healthy adult male SD rats showed that the average deviation between EIT-localized and EEG-topography centroids was 0.13 mm,with a 6.37%rel-ative error.Moreover,the area was confirmed by histopathology to have typical features of epileptic lesions,indicating that EIT has the feasibility of accurately locating EZ.The research can offer a new method for precise EZ localization and significance for improving the success rate of epilepsy treatment.关键词
电阻抗断层成像/脑电图/同步系统/致痫灶定位/滤波Key words
Electrical impedance tomography/Electroencephalogram/Synchronous detection system/Epileptogenic zone localiza-tion/Filter分类
医药卫生引用本文复制引用
朱文静,吴欣雨,杨敬荣,陈诚,吴冠,杨方,王蕾..电阻抗断层成像与脑电同步检测系统研发及其在癫痫病灶定位中的可行性研究[J].生物医学工程研究,2026,45(1):7-14,8.基金项目
陕西省重点研发计划(2024SF-YBXM-451) （2024SF-YBXM-451）
西京医院医务人员培养交叉融合专项(XJZT24JC29). （XJZT24JC29）
