日用化学品科学2026，Vol.49Issue(4)：34-40,7.DOI:10.3969/j.issn.1006-7264.2026.04.006
响应面法优化金线莲苷提取工艺及其抗氧化活性研究
Optimization of Kinsenoside extraction using response surface methodology and evaluation of its antioxidant activity
摘要
Abstract
To optimize the extraction of Kinsenoside,ultrasound-assisted ethanol extraction was applied,and conditions were optimized using single-factor experiments and response surface methodology.The optimized parameters were ethanol concentration 13%,ultrasound temperature 47℃,ultrasound time 34 min,and solid-to-liquid ratio 1∶20,yielding an extraction rate of 24.81%.Stability tests showed that after 30 days of high temperature or light exposure,glycoside content decreased by 21.89%and 29.52%,respectively.Antioxidant activity assays indicated IC50 values of 1.16,1.40,and 11.61 mg/mL for scavenging DPPH,ABTS,and hydroxyl radicals,respectively,demonstrating strong antioxidant activity.These findings provide a theoretical basis for the development and application of Kinsenoside in cosmetics.关键词
金线莲苷/抗氧化/响应面法/化妆品Key words
Kinsenoside/antioxidant/response surface methodology/cosmetics分类
化学化工引用本文复制引用
叶童妹,王磊,谢高宝,邹洁,戴伟鹏,陈来成..响应面法优化金线莲苷提取工艺及其抗氧化活性研究[J].日用化学品科学,2026,49(4):34-40,7.基金项目
金线莲深加工与化妆品应用研究与产业化(2023440111002747) （2023440111002747）
