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基于液滴微流控技术的水凝胶材料及其在类器官中的应用研究进展

冯国萌 王恩民 王思媛 王若雨 于炜婷

生物医学工程研究2026,Vol.45Issue(1):58-64,7.
生物医学工程研究2026,Vol.45Issue(1):58-64,7.DOI:10.19529/j.cnki.1672-6278.2026.01.09

基于液滴微流控技术的水凝胶材料及其在类器官中的应用研究进展

Research progress on hydrogel materials based on droplet microfluidic technology and their application in organoids structure

冯国萌 1王恩民 1王思媛 1王若雨 1于炜婷2

作者信息

  • 1. 大连大学附属中山医院肿瘤实验室,大连 116001
  • 2. 大连大学附属中山医院中心实验室,大连 116001
  • 折叠

摘要

Abstract

Organoid culture has long been confronted with bottlenecks such as complex operation,poor uniformity,high cost and low throughput.Droplet microfluidics equipped with novel hydrogel materials provides a new strategy due to its advantages of high throughput,good repeatability and retention of heterogeneity.This article systematically reviews the progress of hydrogel materials based on droplet microfluidic technology and their applications in organoids.Then,it analyzes the future development directions of integrated integration of droplet microfluidic platforms,dynamic responsiveness regulation of hydrogel materials,and supporting high-throughput analysis technologies to provide new research ideas and technical platforms for new drug development,precision medicine and regenera-tive medicine.

关键词

液滴微流控/水凝胶/类器官/高通量筛选/再生医学

Key words

Droplet microfluidics/Hydrogel/Organoid/High-throughput screening/Regenerative medicine

分类

医药卫生

引用本文复制引用

冯国萌,王恩民,王思媛,王若雨,于炜婷..基于液滴微流控技术的水凝胶材料及其在类器官中的应用研究进展[J].生物医学工程研究,2026,45(1):58-64,7.

基金项目

国家自然科学基金项目(82172822). (82172822)

生物医学工程研究

1672-6278

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