医药导报2026，Vol.45Issue(4)：617-624,8.DOI:10.3870/j.issn.1004-0781.2026.04.009
复方丹参滴丸治疗糖尿病视网膜病变的药效物质基础和作用机制研究进展
Research Progress on the Pharmacodynamic Material Basis and Mechanisms of Compound Danshen Dripping Pills in the Treatment of Diabetic Retinopathy
摘要
Abstract
The pharmacological effects of compound Danshen dripping pills(CDDP)in the treatment of diabetic reti-nopathy(DR)are attributed to various bioactive constituents,including saponins,phenolic acids,and diterpene quinones.Re-searches indicate that CDDP exerts therapeutic effects against DR through multiple pathways,such as protecting vascular endothelial cells,inhibiting pathological neovascularization,improving hemorheology,regulating blood lipid levels,and promoting the repair of retinal microstructure.However,the precise mechanisms underlying its preventive and therapeutic actions in DR remain incom-pletely understood.This review provides an overview of recent advances in the pharmacodynamic material basis,pharmacological activities,and associated mechanisms of CDDP.It aims to offer a scientific foundation for the clinical application and further de-velopment of CDDP,as well as for the research and development of novel therapies for diabetic retinopathy.关键词
复方丹参滴丸/糖尿病视网膜病变/药效物质基础/作用机制Key words
Compound Danshen dripping pills/Diabetic retinopathy/Pharmacodynamic material basis/Mechanism of action分类
医药卫生引用本文复制引用
毛樱潞,郑颖,高艳华,安若凡,周强,杨维..复方丹参滴丸治疗糖尿病视网膜病变的药效物质基础和作用机制研究进展[J].医药导报,2026,45(4):617-624,8.基金项目
四大慢病重大专项(2023ZD0509300) （2023ZD0509300）
中国中医科学院科技创新工程资助项目(CI2023E002) （CI2023E002）
中央级公益性科研院所基本科研业务费专项资金资助项目(ZXKT25014). （ZXKT25014）
