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Isoquercitrin Improves Insulin Resistance by Inhibiting PTP1B-Regulated IRS/PI3K/AKT Signaling Pathway

LIU Si-yu YU Lu-jing ZHANG Sheng-nan YUE Jia-kui JIANG Guo-jun LU Si-hua LI Ying-jia MENG Jun-yu HUANG Gui-hong

中国结合医学杂志（英文版）2026，Vol.32Issue(4)：340-349,10.

中国结合医学杂志（英文版）2026，Vol.32Issue(4)：340-349,10.DOI:10.1007/s11655-025-3934-6

Isoquercitrin Improves Insulin Resistance by Inhibiting PTP1B-Regulated IRS/PI3K/AKT Signaling Pathway

LIU Si-yu ¹YU Lu-jing ²ZHANG Sheng-nan ³YUE Jia-kui ³JIANG Guo-jun ³LU Si-hua ²LI Ying-jia ²MENG Jun-yu ²HUANG Gui-hong⁴

作者信息

1. Department of Pharmacy,the Second Affiliated Hospital of Guilin Medical University,Guilin,Guangxi Zhuang Autonomous Region(541199),China||School of Pharmacy,Guilin Medical University,Guilin,Guangxi Zhuang Autonomous Region(541199),China||Department of Pharmacy,Heilongjiang Provincial Hospital,Harbin(150000),China
2. Department of Pharmacy,the Second Affiliated Hospital of Guilin Medical University,Guilin,Guangxi Zhuang Autonomous Region(541199),China||School of Pharmacy,Guilin Medical University,Guilin,Guangxi Zhuang Autonomous Region(541199),China
3. Department of Pharmacy,the Second Affiliated Hospital of Guilin Medical University,Guilin,Guangxi Zhuang Autonomous Region(541199),China
4. Department of Pharmacy,the Second Affiliated Hospital of Guilin Medical University,Guilin,Guangxi Zhuang Autonomous Region(541199),China||Guangxi Health Commission Key Laboratory of Glucose and Lipid Metabolism Disorders||Key Laboratory of Diabetic Systems Medicine,the Second Affiliated Hospital of Guilin Medical University,Guilin,Guangxi Zhuang Autonomous Region(541199),China||Guangxi Key Laboratory of Drug Discovery and Optimization||Guangxi Engineering Research Center for Pharmaceutical Molecular Screening and Druggability Evaluation,School of Pharmacy,Guilin Medical University,Guilin,Guangxi Zhuang Autonomous Region(541199),China
折叠

摘要

关键词

insulin resistance/isoquercitrin/Chinese medicine/protein tyrosine phosphatase 1B/insulin receptor substrate/phosphatidylinositol-3-kinase/protein kinase B signal pathway

Key words

insulin resistance/isoquercitrin/Chinese medicine/protein tyrosine phosphatase 1B/insulin receptor substrate/phosphatidylinositol-3-kinase/protein kinase B signal pathway

引用本文复制引用

LIU Si-yu,YU Lu-jing,ZHANG Sheng-nan,YUE Jia-kui,JIANG Guo-jun,LU Si-hua,LI Ying-jia,MENG Jun-yu,HUANG Gui-hong..Isoquercitrin Improves Insulin Resistance by Inhibiting PTP1B-Regulated IRS/PI3K/AKT Signaling Pathway[J].中国结合医学杂志（英文版）,2026,32(4):340-349,10.

基金项目

Supported by National Natural Science Foundation of China(No.82160701) （No.82160701）

Guangxi Natural Science Foundation(No.2025GXNSFAA069059) （No.2025GXNSFAA069059）

Medical Science Research Fund of Beijing Health Alliance Charitable Foundation(No.KM226002) （No.KM226002）

and Guilin Medical University Master's Research Project(No.GYYK2022004) （No.GYYK2022004）

中国结合医学杂志（英文版）

ISSN：1672-0415

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