中国兽药杂志2026，Vol.60Issue(3)：51-56,6.DOI:10.11751/ISSN.1002-1280.2026.3.08
地洛瑞林植入剂在犬猫生殖调控上的应用前景
Application Prospect of Delorelin Implant in Reproductive Regulation of Dogs and Cats
裘丞军 1侯轩 1蔡文金 1刘靥 1屈健1
作者信息
- 1. 浙江省动物疫病预防控制中心,杭州 311199
- 折叠
摘要
Abstract
Delorelin,as an analog of gonadotropin-releasing hormone(GnRH)in peptide hormones,can inhibit the pituitary-gonadal axis through sustained low dose release,affect the synthesis and/or release of follicle-stimulating hormone(FSH)and luteinizing hormone(LH),and then regulate the reproductive ability of male animals.In 2007,the Veterinary Drug Committee(CVMP)of the European Drug Administration(EMA)approved the deslorelin acetate implant for the temporary treatment of male infertility in cats and dogs,as well as temporary infertility in female cats,which was the first time that the drug was used in dogs and cats.In 2019,The Ministry of Agriculture and Rural Affairs approved the 4.7 mg delorelin acetate implant from VIRBAC of France for the temporary birth control of healthy,sexually mature and non-castrated male dogs,and the drug entered the Chinese market for the first time.In this paper the mechanism of action,pharmacokinetic properties,clinical application and development prospects of dilorelin in dogs and cats were reviewed,in order to promote the research,development and application of dilorelin in China.关键词
地洛瑞林植入剂/犬/猫/生殖调控/应用前景Key words
delorelin implant/dog/cat/reproductive regulation/application prospect分类
农业科技引用本文复制引用
裘丞军,侯轩,蔡文金,刘靥,屈健..地洛瑞林植入剂在犬猫生殖调控上的应用前景[J].中国兽药杂志,2026,60(3):51-56,6.
