中山大学学报（医学科学版）2026，Vol.47Issue(2)：379-386,8.DOI:10.11714/jsysu.med.YX20250173
Klippel-Trenaunay综合征伴消化道出血的临床特征分析
Analysis of Clinical Characteristics of Klippel-Trenaunay Syndrome with Gastrointestinal Bleeding
摘要
Abstract
[Objective]To investigate the clinical characteristics of a child with Klippel-Trenaunay syndrome(KTS)complicated by lower gastrointestinal bleeding,for better understanding of this rare condition.[Methods]A retrospective analysis was conducted on the clinical data of a pediatric KTS case with lower gastrointestinal bleeding admitted to the Department of Gastroenterology of the Affiliated Women and Children's Medical Center of Guangzhou Medical University in October 2024.Using"Klippel-Trenaunay Syndrome""KTS""Gastrointestinal Bleeding"as keywords,we searched for relevant literature in the Wanfang Chinese Database and PubMed database up to March 2025 in our analysis.[Results]The 8-year-old boy was admitted with a 4-year history of hematochezia that had worsened over the previous two weeks.He had been previously diagnosed with KTS in outpatient consultation for lower limb asymmetry.Gastrointestinal endoscopy revealed diffuse,tortuous,bluish-purple vessels in the mucosa from the sigmoid colon to the distal rectum.Oral polyethylene glycol and thalidomide significantly improved his hematochezia during follow-up.[Conclusion]KTS often involves multiple systems in children,requiring multidisciplinary collaboration.Comprehensive diagnostic procedures such as gastrointestinal endoscopy are essential for formulating individualized treatment plans.Thalidomide may play an active role in managing vascular malformations in the intestine,offering a promising therapeutic approach.关键词
Klippel-Trenaunay综合征/肠血管畸形/下消化道出血/消化内镜检查/沙利度胺Key words
Klippel-Trenaunay syndrome/intestinal vascular malformation/lower gastrointestinal bleeding/digestive endoscopy examination/thalidomide分类
医药卫生引用本文复制引用
李木生,刘瑞桃,袁林清,王洪丽..Klippel-Trenaunay综合征伴消化道出血的临床特征分析[J].中山大学学报（医学科学版）,2026,47(2):379-386,8.基金项目
广州市科技计划项目(2025A03J4366) （2025A03J4366）
