中国医院用药评价与分析2026，Vol.26Issue(3)：266-269,4.DOI:10.14009/j.issn.1672-2124.2026.03.003
基于功效的中药妊娠期风险评估与分析
Risk Assessment and Analysis of Traditional Chinese Medicine During Pregnancy Based on Efficacy Evaluation
摘要
Abstract
OBJECTIVE:To analyze the efficacy of traditional Chinese medicine related to pregnancy risks,and evaluate the pregnancy risks of traditional Chinese medicine based on contraindicated traditional Chinese medicine during pregnancy listed in Part Ⅰ of Pharmacopoeia of the People's Republic of China(2025 edition,hereinafter referred to as"Chinese Pharmacopoeia").METHODS:Based on the data of traditional Chinese medicine recorded in Chinese Pharmacopoeia,the basic efficacy of each traditional Chinese medicine was separated and formed,combined with the contraindications of traditional Chinese medicine in pregnancy,the risk and efficacy of traditional Chinese medicine in pregnancy were analyzed by statistical methods.RESULTS:Among the 616 kinds of traditional Chinese medicine recorded in Chinese Pharmacopoeia,353 kinds of basic efficacy were sorted out,of which 17 kinds of efficacy were significantly correlated with pregnancy risk(P<0.05).In addition to 38 kinds of contraindicated traditional Chinese medicines in Chinese Pharmacopoeia,113 kinds of traditional Chinese medicines with pregnancy risks and 13 kinds of traditional Chinese medicines with anti-abortion effect were evaluated based on the risk and efficacy of pregnancy.CONCLUSIONS:Based on efficacy evaluation of pregnancy risk,the pregnancy risk of traditional Chinese medicine can be effectively evaluated,which can provide reference for the further construction of the safety evaluation system of traditional Chinese medicine and Chinese patent medicine during pregnancy.关键词
中药/功效/中成药/妊娠期/风险评估Key words
Traditional Chinese medicine/Efficacy/Chinese patent medicine/Pregnancy/Risk evaluation分类
医药卫生引用本文复制引用
杜博冉,史湘君,张雪艳,王建东,冯欣..基于功效的中药妊娠期风险评估与分析[J].中国医院用药评价与分析,2026,26(3):266-269,4.基金项目
国家自然科学基金青年项目(No.72204170) （No.72204170）
首都卫生发展专项(No.首发2024-2-2115) （No.首发2024-2-2115）
中国药学会医院药学专业委员会医院药学科研专项资助项目(No.CPA-Z05-ZC-2022-002) （No.CPA-Z05-ZC-2022-002）
中华医学会临床药学分会2023年度临床药学青年项目(No.Z-2021-46-2101-2023) （No.Z-2021-46-2101-2023）
