中药与临床2026，Vol.17Issue(2)：29-36,8.
7种口服中成药治疗脑卒中恢复期有效性和安全性的网状Meta分析
Network meta-analysis of the efficacy and safety of 7 oral Chinese patent medicines in the treatment of stroke recov-ery period
贾梦婷 1李邦艳 1李芷芮 1杨胜 1徐瑶 1王世宇2
作者信息
- 1. 成都中医药大学药学院,四川成都 611137
- 2. 成都中医药大学公共卫生学院,四川成都 611137
- 折叠
摘要
Abstract
Objective:To evaluate the efficacy and safety of 7 kinds of Chinese patent medicines combined with conven-tional western medicine in the treatment of patients with stroke recovery,and to provide evidence-based basis for clinical decision-making optimization.Methods:The evaluation was performed based on network meta-analysis,and the statistical analysis of data results was conducted using R language packages.Results:A total of 19 RCTs were included,involving 1 832 patients.The re-sults of effectiveness analysis showed that(1)in terms of total effective rate,Tongxinluo capsule combined treatment had the best curative effect(SUCRA=0.3873);(2)In terms of improvement of NIHSS and ALD:Nao'an capsule combined treatment was the most significant(SUCRA=0.693 5;SUCRA=0.389 1);(3)In terms of TCM syndrome score and mRS score:Duzhi pill combined treatment had statistical advantages(MD=4.87,95％CI=-1.46-11.22;MD=1.12,95％CI=0.21-2.01);(4)In terms of Safety analy-sis:Duzhi Pills combined with CT had the lowest risk of adverse reactions(SUCRA=0.745 2).Conclusion:Combined therapy with seven kinds of Chinese patent medicines can improve neurological function and daily living ability in patients during the re-covery stage of stroke,among which Tongxinluo Capsule,Nao'an Capsule and Duzhi Pill exhibited prominent efficacy with spe-cific outcome indicators.关键词
中成药/脑卒中恢复期/网状Meta分析/有效性/安全性Key words
Chinese patent medicine/stroke recovery period/network Meta-analysis/efficacy/safety分类
医药卫生引用本文复制引用
贾梦婷,李邦艳,李芷芮,杨胜,徐瑶,王世宇..7种口服中成药治疗脑卒中恢复期有效性和安全性的网状Meta分析[J].中药与临床,2026,17(2):29-36,8.
