中药与临床2026，Vol.17Issue(2)：37-44,8.
基于本草考证和文献计量学的花椒止痒功效研究
Research on the antipruritic effect of Zanthoxyli Pericarpium based on the herbal textual and bibliometrics
摘要
Abstract
Objective:To study the antipruritic effect of Zanthoxyli Pericarpium by systematically combing ancient and mod-ern literature.Methods:The traditional application of antipruritic effect of Zanthoxyli Pericarpium was sorted out and analyzed by consulting ancient herbal books of past dynasties.Bibliometrics was further used to summarize the literature records of Zan-thoxyli Pericarpium insecticidal antipruritic,and VOSviewer software was used to analyze the keywords,so as to provide scien-tific demonstration and literature reference for its subsequent basic research and clinical application.Results:In this study,com-bined with literature research and modern data analysis,it was found that the antipruritic application of Zanthoxyli Pericarpium be-gan in the Southern and Northern Dynasties,mainly based on killing insects,and expanded to a variety of pruritus diseases in the Ming and Qing Dynasties,forming a theoretical system of"A expelling wind,killing insects,drying dampness and detoxifica-tion".Modern research showed that eczema,atopic dermatitis and psoriasis were hot diseases.Zanthoxyli Pericarpium was a high-frequency antipruritic drug,which was often combined with heat-clearing and dampness-drying drugs for damp-heat skin dis-eases,reflecting the characteristics of"warm-dry synergy".The application history of Zanthoxyli Pericarpium reflected the cog-nitive evolution from simple practice to theoretical systematization,from single insecticide to overall syndrome differentiation and treatment of damp-heat.Conclusion:Its external use characteristics of Zanthoxyli Pericarpium also reflect the wisdom of drug use according to different drugs.This study can provide historical and modern theoretical support for the modern clinical application of insecticidal antipruritic effect,and help to promote the modern research and application practice of traditional Chinese medicine in the treatment of specific skin diseases.关键词
中药/花椒/止痒/文献考证/文献计量学Key words
Traditional Chinese medicine/Zanthoxyli Pericarpium/antipruritic/literature research/bibliometrics分类
医药卫生引用本文复制引用
白玉如,陈炎艳,王茜,吴纯洁,彭伟,黎量,张萌萌..基于本草考证和文献计量学的花椒止痒功效研究[J].中药与临床,2026,17(2):37-44,8.基金项目
国家自然科学基金(82304972) （82304972）
四川省中医药管理局2020年度花椒药用价值研发专项(2020HJZX001) （2020HJZX001）
四川中医药大健康产业发展与乡村振兴研究中心项目(DJKYB202306) （DJKYB202306）
