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"气化五行"视角下五脏-线粒体功能映射关系的构建

段晨阳 柏力萄 魏军平 谭旭鑫 廖海棠 贡磊磊 肖林含 刘瑞雪 潘欣渝 李俊

中医杂志2026,Vol.67Issue(6):589-595,7.
中医杂志2026,Vol.67Issue(6):589-595,7.DOI:10.13288/j.11-2166/r.2026.06.001

"气化五行"视角下五脏-线粒体功能映射关系的构建

Construction of the Mapping Frameword of the Five Zang(脏)Organs and the Mitochondrial Function Based on the"Qi Transformation into the Five Phases"Theory

段晨阳 1柏力萄 1魏军平 2谭旭鑫 1廖海棠 3贡磊磊 4肖林含 5刘瑞雪 1潘欣渝 2李俊6

作者信息

  • 1. 重庆医科大学附属第二医院,重庆市渝中区临江门路76号,400010
  • 2. 中国中医科学院广安门医院
  • 3. 重庆市中医院
  • 4. 首都医科大学附属北京妇产医院
  • 5. 北京中医药大学
  • 6. 上海市中医医院
  • 折叠

摘要

Abstract

Based on"qi transforming into the five phases"theory,this study constructs a conceptual correspon-dence between the five zang(脏)organs and mitochondrial function in modern medicine,with mitochondrial quality control(MQC)serving as the core regulatory mechanism to interpret the fucntions of zang organs.Through theoretical synthesis and cross-system structural mapping,a five zang organs-mitochondrial functional mapping framework is pro-posed.In this framework,the spleen is aligned with mitochondrial metabolic networks,while the kidney with mito-chondrial genetics and energy transfer,the liver with mitochondrial metabolic regulation and detoxification,the heart with cardiomyocyte mitochondrial density and metabolic activity,and the lung with mitochondrial redox regulation and signaling control.Furthermore,the intrinsic associations between the physiological characteristics of the five zang organs and the MQC system are identified,which is manifested as structural correspondence and regulatory coordina-tion between zang organ functional activities and mitochondrial homeostasis.

关键词

气化五行/五脏/线粒体/能量代谢

Key words

qi transforming into the five phases/five zang(脏)organs/mitochondria/energy metabolism

引用本文复制引用

段晨阳,柏力萄,魏军平,谭旭鑫,廖海棠,贡磊磊,肖林含,刘瑞雪,潘欣渝,李俊.."气化五行"视角下五脏-线粒体功能映射关系的构建[J].中医杂志,2026,67(6):589-595,7.

基金项目

国家自然科学基金(82472182,82205049) (82472182,82205049)

中国博士后科学基金第73批面上项目资助(2023MD734188) (2023MD734188)

重庆市杰出青年基金(CSTB2025NSCQ-JQX0019) (CSTB2025NSCQ-JQX0019)

重庆市自然科学基金(CSTB2024NSCQ-MSX0189) (CSTB2024NSCQ-MSX0189)

重庆医科大学青年拔尖人才项目 ()

中医杂志

1001-1668

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