中医临床研究2026，Vol.18Issue(1)：56-63,8.DOI:10.3969/j.issn.1674-7860.2026.01.008
235例卵巢癌术后患者中医证型与体质类型分布规律及相关性研究
A study on the distribution patterns and correlation of TCM syndrome types and constitution types in 235 postoperative patients with ovarian cancer
摘要
Abstract
Objective:To explore the traditional Chinese medicine(TCM)syndrome types,constitution types and common clinical symptoms of patients with ovarian cancer after surgery,and to provide a reference basis for the TCM clinical-syndrome differentiation and treatment of these patients.Methods:A cross-sectional study was conducted to investigate the clinical data of 235 patients with ovarian cancer who were newly diagnosed and treated at the Affiliated Hospital of Shanghai University of Traditional Chinese Medicine.The baseline clinical data,TCM syndrome types,constitution types and common clinical symptoms of the patients were studied.Results:The distribution of TCM syndrome types in 235 patients with ovarian cancer was as follows:spleen-kidney Yang(阳)deficiency type(62.55%),Qi(气)and Yin(阴)deficiency type(11.06%),Qi and blood deficiency type(10.21%),Qi stagnation and blood stasis type(7.66%),damp-heat and toxin accumulation type(3.40%),phlegm-dampness accumulation type(2.98%),and cold coagulation and blood stasis type(2.13%).The proportion of constitution types was as follows:Yang deficiency type(37.45%),Qi depression type(28.09%),blood stasis type(11.49%),Qi deficiency type(7.23%),Yin deficiency type(5.11%),balanced type(5.53%),damp-heat type(2.98%),and phlegm-dampness type(2.13%).Chi-square test was used for analysis,and there was a significant correlation between the two(P<0.001).The common clinical symptoms were fatigue(50.64%),easy awakening(48.51%),numbness of hands and feet(40.43%),insomnia(37.87%),spiritlessness(34.47%),sweating(32.77%),hot flushes(30.64%),frequent dreams(30.21%),cold intolerance(23.83%),constipation(22.55%),joint pain(22.55%),abdominal distension(16.60%),and frequent nocturia(15.74%).There were statistically significant differences in the incidence of easy awakening,insomnia,cold intolerance,and sweating among patients with different TCM syndrome types of ovarian cancer(P<0.05).There were statistically significant differences in the incidence of frequent nocturia and insomnia among patients with different constitution types of ovarian cancer(P<0.05).Conclusion:The distribution of TCM syndrome types and constitution types in patients with ovarian cancer after surgery is regular and closely related.The core pathogenesis is liver and kidney deficiency as the root cause,and Qi stagnation and blood stasis as the branch cause.In clinical practice,integrated syndrome and constitution differentiation should be carried out based on the common symptom clusters of patients with ovarian cancer after surgery,and individualized treatment strategies of"strengthening the body and consolidating the root,taking into account the branch causes,and regulating both body and spirit"should be formulated to achieve more precise intervention.关键词
卵巢癌/中医证型/体质/术后/分布规律Key words
Ovarian cancer/TCM syndrome types/Constitution/Postoperative/Distribution regularity分类
医药卫生引用本文复制引用
姚嘉良,张龙,田建辉,陆鑫熠,杨蕴..235例卵巢癌术后患者中医证型与体质类型分布规律及相关性研究[J].中医临床研究,2026,18(1):56-63,8.基金项目
四大慢病重大专项(2024ZD0521402) （2024ZD0521402）
上海市科学技术委员会2025年度关键技术研发计划"医学创新研究"项目(25Y12800600) （25Y12800600）
上海申康医院发展中心第二轮《促进市级医院临床技能与临床创新三年行动计划》研究型医师创新转化能力培训项目(SHDC2023CRD01) （SHDC2023CRD01）
国家自然科学青年基金项目(82305069) （82305069）
上海市静安区卫生科研课题(2023QT02). （2023QT02）
