首页|期刊导航|Oncology Research|SDHA Deficiency in Hepatocellular Carcinoma Promotes Tumor Progression through Succinate-Induced M2 Macrophage Polarization

SDHA Deficiency in Hepatocellular Carcinoma Promotes Tumor Progression through Succinate-Induced M2 Macrophage Polarization

Xinyang Li Luyuan Ma Chuan Shen Ruolan Gu Shilong Dong Mingjie Liu Ying Xiao Wenpeng Liu Yuexia Liu Caiyan Zhao

Oncology Research2026，Vol.34Issue(2)：P.592-617,26.

Oncology Research2026，Vol.34Issue(2)：P.592-617,26.DOI:10.32604/or.2025.073179

SDHA Deficiency in Hepatocellular Carcinoma Promotes Tumor Progression through Succinate-Induced M2 Macrophage Polarization

Xinyang Li ¹Luyuan Ma ¹Chuan Shen ¹Ruolan Gu ¹Shilong Dong ¹Mingjie Liu ¹Ying Xiao ¹Wenpeng Liu ¹Yuexia Liu ¹Caiyan Zhao¹

作者信息

1. Department of Infectious Diseases,Hebei Medical University Third Hospital,Shijiazhuang,050000,China Clinical Research Center for Infectious Disease of Hebei Province,Shijiazhuang,050000,China Hebei Key Laboratory for Diagnosis,Treatment,Emergency Prevention and Control of Critical Infectious Diseases,Shijiazhuang,050000,China
折叠

摘要

关键词

Hepatocellular carcinoma/metabolic reprogramming/tumor microenvironment/succinate/M2 macrophage/succinate dehydrogenase complex subunit A(SDHA)/G protein-coupled receptor 91(GPR91)

分类

医药卫生

引用本文复制引用

Xinyang Li,Luyuan Ma,Chuan Shen,Ruolan Gu,Shilong Dong,Mingjie Liu,Ying Xiao,Wenpeng Liu,Yuexia Liu,Caiyan Zhao..SDHA Deficiency in Hepatocellular Carcinoma Promotes Tumor Progression through Succinate-Induced M2 Macrophage Polarization[J].Oncology Research,2026,34(2):P.592-617,26.

基金项目

supported by the Central Government-Guided Local Science and Technology Development Fund Project(Science and Technology Innovation Base Project)(Grant No.236Z7749G) （Science and Technology Innovation Base Project）

Hebei Provincial Precision Medicine Innovation and Development Joint Fund Incubation Project(Grant No.H2025206547) （Grant No.H2025206547）

Hebei Provincial Basic Research Special Youth Science Fund Project(Grant No.H2025206274). （Grant No.H2025206274）

Oncology Research

ISSN：0965-0407

访问量1

下载量0

段落导航