首页|期刊导航|Traditional Medicine Research|Dioscorea bulbifera L.induces liver injury in mice partly through bile acids metabolic disorders and gut microbiota dysbiosis mediated by the YY1-FXR/Nrf2 signaling pathway

Dioscorea bulbifera L.induces liver injury in mice partly through bile acids metabolic disorders and gut microbiota dysbiosis mediated by the YY1-FXR/Nrf2 signaling pathway

Bo-Shen Zhao Yun-Dong Xie Xin Wang Yu-Han Zhang Hong-Zhe Zhu Lei-Lei Shi Hui-Zi Shangguan Ling Ding Shu-Hong Zhu Cui-Cui Ren Ji-Ping Liu

Traditional Medicine Research2026，Vol.11Issue(8)：P.15-27,13.

Traditional Medicine Research2026，Vol.11Issue(8)：P.15-27,13.DOI:10.53388/TMR20251026001

Dioscorea bulbifera L.induces liver injury in mice partly through bile acids metabolic disorders and gut microbiota dysbiosis mediated by the YY1-FXR/Nrf2 signaling pathway

Bo-Shen Zhao ¹Yun-Dong Xie ¹Xin Wang ¹Yu-Han Zhang ¹Hong-Zhe Zhu ¹Lei-Lei Shi ¹Hui-Zi Shangguan ¹Ling Ding ¹Shu-Hong Zhu ²Cui-Cui Ren ²Ji-Ping Liu³

作者信息

1. Department of Pharmacology,Shaanxi University of Chinese Medicine,Xianyang 712046,China
2. Department of Pharmacy,First Hospital of Xi''an,Xi''an 710002,China
3. Department of Pharmacology,Shaanxi University of Chinese Medicine,Xianyang 712046,China Key Laboratory of Pharmacodynamic Mechanism and Material Basis of Traditional Chinese Medicine,Shaanxi Administration of Traditional Chinese Medicine,Xianyang 712046,China Engineering Research Center of Brain Health Industry of Chinese Medicine,Universities of Shaanxi Province,Xianyang 712046,China
折叠

摘要

关键词

Dioscorea/bulbifera/L./liver/injury/bile/acids/metabolism/gut/microbiota/short-chain/fatty/acids

分类

医药卫生

引用本文复制引用

Bo-Shen Zhao,Yun-Dong Xie,Xin Wang,Yu-Han Zhang,Hong-Zhe Zhu,Lei-Lei Shi,Hui-Zi Shangguan,Ling Ding,Shu-Hong Zhu,Cui-Cui Ren,Ji-Ping Liu..Dioscorea bulbifera L.induces liver injury in mice partly through bile acids metabolic disorders and gut microbiota dysbiosis mediated by the YY1-FXR/Nrf2 signaling pathway[J].Traditional Medicine Research,2026,11(8):P.15-27,13.

基金项目

supported by the National Natural Science Foundation of China(82204790) （82204790）

Shaanxi University of Chinese Medicine Science and Technology Program(2024-LJRC-04) （2024-LJRC-04）

Shaanxi Province Natural Science Foundation(2024JC-YBMS-759) （2024JC-YBMS-759）

Qinchuangyuan TCM Industry Innovation Project(L2024-QCY-ZYYJJQ-X29). （L2024-QCY-ZYYJJQ-X29）

Traditional Medicine Research

ISSN：2413-3973

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