阿尔茨海默病及相关病2026，Vol.9Issue(2)：135-138,144,5.DOI:10.3969/j.issn.2096-5516.2026.02.011
步态相关数字化诊断标志物对早期识别阿尔茨海默病的应用价值
The application values of gait-related digital diagnostic markers for the early detection of Alzheimer's disease
摘要
Abstract
Gait abnormalities have long been regarded as exclusion criteria for Alzheimer's disease(AD).However,with advances in modern gait-analysis research,this traditional view is being overturned.Modern gait analysis,which integrates wearable sensors,computer vision,and artificial-intelligence algorithms,now generates gait parameters that already support the early,accurate,and dynamic detection of abnormal gait patterns.This paper reviews the mechanisms underlying gait disturbances in AD,integrating them with the cerebral pathological evolution characteristic of the disorder.We provide a comprehensive overview of progress in gait-analysis research in AD,with particular emphasis on studies linking digitized gait parameters to biological diagnostic markers(BDMs),aiming to evaluate the application values of gait-related digital diagnostic markers(DDMs)for the early identification of AD.关键词
阿尔茨海默病/步态分析/数字化诊断标志物/早期识别Key words
Alzheimer's disease/Gait analysis/Digital diagnostic biomarkers/Early identification分类
医药卫生引用本文复制引用
火婉颖,刘巍,许若琳,徐武华..步态相关数字化诊断标志物对早期识别阿尔茨海默病的应用价值[J].阿尔茨海默病及相关病,2026,9(2):135-138,144,5.基金项目
广州市卫健委特色技术项目(2023C-TS07) （2023C-TS07）
广州市科技局市校联合项目(2023A03J0532) （2023A03J0532）
广州市科技局市校联合项目(2023A03J0608) （2023A03J0608）
