摘要
Abstract
Objective To explore the distribution characteristics of corneal volume(CV)and its correlation with ocular biological parameters in adolescents with myopia.Methods A total of 110 adolescent patients who underwent myopia examination in The Third People's Hospital of Chengdu from September 2023 to March 2024 were collected by random stratified sampling,and were divided into the younger age group(10-17 years,n=46)and the older age group(18-24 years,n=64)according to their age groups.According to the degree of myopia,they were divided into mild myopia group(SE＜-3.00D,n=52),moderate myopia group(-3.00D≤SE≤-6.00D,n=36)and high myopia group(SE＞-6.00D,n=22).Centered on the corneal apex,the corneal region with diameters of 3 mm,5 mm,and 7 mm was measured.The biological parameters of the eyeballs and CV of adolescent myopia patients of different ages and degrees of myopia were compared.Spearman correlation analysis was used to evaluate the association between CV and other ocular biological indicators.The restricted cubic spline(RCS)fitting regression model was used to explore the relationship between other ocular biological parameters and CV.The P-value and the Pn value of the test cube term parameters were used to determine whether the nonlinear model with the cube term was statistically significant.Results The corneal curvature,axial length,refraction,radius of corneal curvature,CV-3 mm,CV-5 mm,and CV-7 mm in the older age group were higher than those in the younger age group,and the lens thickness was lower than that in the younger age group(P＜0.05).The corneal curvature,axial length,refraction,radius of corneal curvature,CV-3 mm,CV-5 mm,and CV-7 mm in the moderate myopia group and the high myopia group were higher than those in the mild myopia group(P＜0.05).Spearman's correlation analysis showed that CV-3 mm,CV-5 mm,and CV-7 mm were significantly positively correlated with central corneal thickness(rCV-3 mm=0.985,rCV-5 mm=0.976,rCV-7 mm=0.956).The results of RCS analysis showed that only the corneal curvature and corneal curvature radius had a nonlinear relationship with CV-3 mm,CV-5 mm,and CV-7 mm(P and Pn＜0.05),and other ocular biological parameters had no nonlinear relationship with CV-3 mm,CV-5 mm,and CV-7 mm.Conclusions With the increase of age and myopia,the corneal curvature,axial length and CV of adolescents increased,and the lens thickness decreased,and the CV was positively correlated with the central corneal thickness,and the corneal curvature had a nonlinear relationship with CV.关键词
青少年/近视人群/角膜体积/眼球生物参数Key words
teenager/myopic population/corneal volume/eye biological parameter分类
医药卫生
