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早期胃癌行前哨淋巴结导航手术的实践与思考

步召德 冯梦宇 季科

北京大学学报(医学版)2026,Vol.58Issue(2):239-243,5.
北京大学学报(医学版)2026,Vol.58Issue(2):239-243,5.DOI:10.19723/j.issn.1671-167X.2026.02.002

早期胃癌行前哨淋巴结导航手术的实践与思考

Practice and reflection on sentinel lymph node navigation surgery for early gastric cancer

步召德 1冯梦宇 2季科2

作者信息

  • 1. 北京大学肿瘤医院暨北京市肿瘤防治研究所胃肠肿瘤中心 消化系肿瘤整合防治全国重点实验室,北京 100142
  • 2. 北京大学肿瘤医院暨北京市肿瘤防治研究所胃肠肿瘤中心 恶性肿瘤发病机制及转化研究教育部重点实验室,北京 100142
  • 折叠

摘要

Abstract

With the continuous update and iteration of minimally invasive techniques,artificial intelli-gence and big data,the surgical treatment of early gastric cancer has gradually entered an era of indivi-dualization,precision and intelligence.Function-preserving surgeries represented by sentinel lymph node navigation surgery have gradually become the mainstream surgical options for early gastric cancer.How-ever,a great deal of controversy remains in sentinel lymph node navigation surgery regarding the definition of sentinel lymph nodes,the selection of tracers,the time of visualization,the scope and strategy of sur-gery,pathological examination,and the indications for supplementary radical surgery after surgery.Based on the current research progress and practical experience,it is suggested to comprehensively determine the sentinel lymph node area based on the lymph node metastasis pattern and the tracer imaging situation,thereby redefining the sentinel lymph nodes of early gastric cancer;It is recommended to select indocya-nine green as the tracer for sentinel lymph node navigation surgery in early gastric cancer,and the defini-tion of the imaging time of indocyanine green still needs further research for confirmation;Regarding the intraoperative frozen pathological examination of the incision margin,it is necessary to pay attention to the complete preservation of the gastric mucosa and try to avoid the ablation margin of the ultrasonic scalpel or electrocautery;Regarding the frozen pathological examination of sentinel lymph nodes during the operation,it is recommended to adopt different sampling methods based on whether the short diameter of the lymph nodes exceeds 4 mm;Based on the previous practical experience,our team has put forward suggestions in aspects such as the sentinel lymph node dissection strategy,the scope and strategy of local gastrectomy,and the indications for supplementary surgery after initial surgery.Therefore,high-quality evidence-based medical research is still needed to verify the safety and effectiveness of sentinel lymph node navigation surgery,thereby improving the surgical treatment level of early gastric cancer in China and even globally.

关键词

早期胃癌/前哨淋巴结导航手术/胃局部切除/安全性/有效性

Key words

Early gastric cancer/Sentinel lymph node navigation surgery/Local gastrectomy/Safety/Effectiveness

分类

医药卫生

引用本文复制引用

步召德,冯梦宇,季科..早期胃癌行前哨淋巴结导航手术的实践与思考[J].北京大学学报(医学版),2026,58(2):239-243,5.

北京大学学报(医学版)

1671-167X

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