磁共振成像2026，Vol.17Issue(3)：168-173,6.DOI:10.12015/issn.1674-8034.2026.03.024
MRI影像组学对原发性中枢神经系统淋巴瘤的鉴别诊断与预后评估的研究进展
Research progress of MRI radiomics in differential diagnosis and prognostic evaluation of primary central nervous system lymphoma
摘要
Abstract
Primary central nervous system lymphoma(PCNSL)is an aggressive extranodal lymphoma that remains clinically rare.Owing to its highly invasive tumor biology and the fact that therapeutic options are constrained by the blood-brain barrier,patients with PCNSL exhibit markedly poor overall prognosis,making PCNSL one of the most challenging lymphoma subtypes in contemporary clinical oncology.Although MRI is now widely used for the diagnosis and grading of central nervous system tumors,the underlying molecular mechanisms,tumor microenvironment,and biological processes within the lesions still require further exploration.Radiomics can mine deeper information from the tumor,enabling more objective and comprehensive assessment of tumor heterogeneity,and has shown great potential for diagnosis,grading,and prognosis prediction across various cancers.This review focuses on the latest applications and research advances of MRI-based radiomics in the diagnosis and prognostic prediction of PCNSL,highlights current limitations,and outlines future research directions,aiming to further advance the field.关键词
原发性中枢神经系统淋巴瘤/磁共振成像/人工智能/影像组学/诊断/预后Key words
primary central nervous system lymphoma/magnetic resonance imaging/artificial intelligence/radiomics/diagnosis/prognosis分类
医药卫生引用本文复制引用
钟琪,崔嘉成,徐东昊,许蕾..MRI影像组学对原发性中枢神经系统淋巴瘤的鉴别诊断与预后评估的研究进展[J].磁共振成像,2026,17(3):168-173,6.基金项目
National Key Clinical Specialty Construction Project(No.Guo Wei Ban Yi Han[2018]292). 国家临床重点专科建设项目(编号:国卫办医函[2018]292号) （No.Guo Wei Ban Yi Han[2018]292）
