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色氨酸代谢网络调控动物生殖系统的研究进展

黄泓杰 王丹 曹随忠 黄逸馨

动物营养学报2026,Vol.38Issue(4):2470-2479,10.
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动物营养学报2026,Vol.38Issue(4):2470-2479,10.DOI:10.12418/CJAN2026.198

色氨酸代谢网络调控动物生殖系统的研究进展

Research Progress on Tryptophan Metabolic Network Regulating in Reproductive System of Animals

黄泓杰 1王丹 1曹随忠 1黄逸馨2

作者信息

  • 1. 四川农业大学动物医学院,成都 611130
  • 2. 四川农业大学动物医学院,成都 611130||四川农业大学农业生物信息教育部重点实验室,成都 611130
  • 折叠

摘要

Abstract

Tryptophan(Trp)and its metabolites are extensively involved in regulating the animal reproductive system through three key metabolic pathways:the kynurenine pathway,the serotonin pathway,and the indole pathway.Current researches indicate that the Trp metabolic network modulates physiological and pathological processes such as pregnancy establishment and reproductive senescence by affecting multiple mechanisms,in-cluding the synthesis and secretion of reproductive hormones,immune microenvironment homeostasis,inflam-matory responses,and antioxidant.This article systematically reviewed recent advances in Trp metabolism within the field of animal reproduction,focusing on its roles in hormonal regulation,immune adaptation,and antioxidant stress response.It aimed to provide insights for a deeper understanding of reproductive regulatory mechanisms and for developing new strategies to improve reproductive efficiency and prevent reproductive dis-orders.[Chinese Journal of Animal Nutrition,2026,38(4):2470-2479]

关键词

色氨酸/生殖功能/犬尿氨酸/血清素/吲哚

Key words

tryptophan/reproductive function/kynurenine/serotonin/indole

分类

农业科技

引用本文复制引用

黄泓杰,王丹,曹随忠,黄逸馨..色氨酸代谢网络调控动物生殖系统的研究进展[J].动物营养学报,2026,38(4):2470-2479,10.

基金项目

四川省自然科学基金青年项目(2024NSFSC1282) (2024NSFSC1282)

国家资助博士后研究人员计划(GZC20231869) (GZC20231869)

动物营养学报

1006-267X

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