法医学杂志2026，Vol.42Issue(1)：49-55,7.DOI:10.12116/j.issn.1004-5619.2023.331003
毛发代谢组学研究及其在法医学领域的应用进展
Research Progress on Hair Metabolomics and Its Application in Forensic Science
摘要
Abstract
Metabolomics is an emerging technology that uses bioinformatics techniques and methods to comprehensively analyze changes in small-molecule metabolites within organisms to identify biomar-kers.In recent years,hair has gradually gained attention in the field of metabolomics.Compared with blood and urine,hair offers a wider detection window and enables retrospective studies.In addition,segmental analysis based on hair growth rates allows hair metabolomics to provide chronological infor-mation on changes in relevant substances.At present,hair metabolomics has established a certain re-search foundation in areas such as monitoring drug abuse,and it shows broad application prospects in forensic applications.This article reviews the collection and processing of hair samples,analytical tech-niques,and their applications in forensic research,with the aim of providing a reference for the fur-ther development of hair metabolomics and its in-depth application across multiple fields.关键词
法医学/代谢组学/毛发/毒物分析/综述Key words
forensic medicine/metabolomics/hair/toxicological analysis/review分类
医药卫生引用本文复制引用
王新颖,张佳丽,向平,王鑫..毛发代谢组学研究及其在法医学领域的应用进展[J].法医学杂志,2026,42(1):49-55,7.基金项目
中央级公益性科研院所资助项目(GY2024G-4) （GY2024G-4）
上海市法医学重点实验室资助项目(21DZ2270800) （21DZ2270800）
