国际口腔医学杂志2026，Vol.53Issue(3)：433-440,8.DOI:10.7518/gjkq.2026104
泛凋亡在口腔疾病中的研究进展
Research progress of PANoptosis in oral diseases
摘要
Abstract
Programmed cell death(PCD)serves as a crucial mechanism for maintaining host innate immunity,homeo-stasis,and the balance between pathogens and the host.PANoptosis is a novel form of programmed cell death that is pri-marily regulated by the PANoptosome complex and concurrently exhibits the features of apoptosis,pyroptosis,and necroptosis.Oral diseases,which significantly impact the quality of life and general health of patients,are a major con-cern.Interest in the underlying mechanisms of PANoptosis involved in oral diseases is currently increasing.This review explains the definition,characteristics,regulatory mechanisms of PANoptosis and its potential relationship with oral di-seases,aiming to offer possible solutions for the detection,prevention,and treatment of oral diseases.关键词
程序性细胞死亡/泛凋亡/泛凋亡复合体/口腔疾病Key words
programmed cell death/PANoptosis/PANoptosome/oral disease分类
医药卫生引用本文复制引用
朱玄德,陈冠辉..泛凋亡在口腔疾病中的研究进展[J].国际口腔医学杂志,2026,53(3):433-440,8.基金项目
National Natural Science Foundation of China(82303794) 国家自然科学基金(82303794) （82303794）
