海南医科大学学报2026，Vol.32Issue(7)：549-560,12.DOI:10.13210/j.cnki.jhmu.20250905.001
黄连解毒汤治疗神经系统疾病的研究进展
Research progress of Huanglian Jiedu Decoction in the treatment of neurological diseases
摘要
Abstract
Huanglian Jiedu Decoction is derived from"Wai Tai Mi Yao"compiled by the renowned doctor Wang Tao.It is widely used in clinical practice and has the effects of clearing heat and detoxifying,purging fire and relieving irritability,as well as calming the mind and stabilizing the will.Neurological diseases,as major diseases that seriously endanger human health,their pre-vention and treatment have always been the difficulties and hotspots in medical research.A large amount of clinical evidence indi-cates that Huanglian Jiedu Decoction has a significant therapeutic effect on a variety of neurological diseases.Experimental studies on this compound and its constituent drugs have initially clarified its pharmacological mechanism of action.However,at present,there is still a lack of a systematic review of its clinical application and mechanism of action.This article systematically reviews the mechanism of action and the current clinical application status of the entire formula of Huanglian Jiedu Decoction and each individu-al ingredient in the treatment of neurological diseases,aiming to provide a scientific basis for the rational clinical application of this formula and a theoretical reference for the in-depth study of its subsequent mechanism of action at the same time.关键词
黄连解毒汤/神经系统疾病/研究进展/临床应用/作用机制Key words
Huanglian Jiedu Decoction/Neurological diseases/Research Progress/Clinical application/Mechanism of ac-tion分类
医药卫生引用本文复制引用
卢柠霞,高澳,杨津津,王业豪,刘树民,卢芳..黄连解毒汤治疗神经系统疾病的研究进展[J].海南医科大学学报,2026,32(7):549-560,12.基金项目
This study was supported by the Noncommunicable Chronic Diseases‑National Science and Technology Major Project(2024ZD0530700) （2024ZD0530700）
the National Natural Science Foundation of China(82374067,82274125) 四大慢病重大专项(2024ZD0530700) （82374067,82274125）
国家自然科学基金项目(82374067,82274125) （82374067,82274125）
