华东理工大学学报（自然科学版）2026，Vol.52Issue(2)：151-167,17.DOI:10.14135/j.cnki.1006-3080.20250513001
巨磁阻(GMR)生物传感器的发展和应用
Development and Application of Giant Magnetoresistance(GMR)Biosensors
摘要
Abstract
As a new type of magnetic sensor,giant magnetoresistance(GMR)biosensor combines GMR effect and immunomagnetic microsphere technology,showing great application potential in biomedical and food safety fields.This paper reviews the basic principles of GMR biosensors,structural technology development,and applications in biomedical and food safety fields.The GMR biosensor realizes the detection of target biomolecules by monitoring the sensitive resistance change caused by the magnetic microsphere field.Its high sensitivity and low detectable concentration characteristics help to achieve quantitative detection of trace target molecules in biological samples.In the biomedical field,GMR biosensors have been applied to the diagnosis of cancer,viral diseases and other diseases,as well as genotyping.In the field of food safety,GMR biosensors are used to detect foodborne toxins and pathogens,as well as other food-related biomarkers.As technology advances,GMR biosensors will play an increasingly important role in ensuring food safety and public health.关键词
巨磁阻生物传感器/结构优化/生物医学诊断/食品安全检测/即时检测Key words
giant magnetoresistance biosensor/structural optimization/biomedical diagnosis/food safety detection/point-of-care testing分类
信息技术与安全科学引用本文复制引用
孙逊,王雨欣,沙金..巨磁阻(GMR)生物传感器的发展和应用[J].华东理工大学学报（自然科学版）,2026,52(2):151-167,17.基金项目
贵州省科技计划项目(黔科合支撑[2022]一般240) （黔科合支撑[2022]一般240）
贵州省科技支撑计划(黔科合支撑[2025]一般091) （黔科合支撑[2025]一般091）
