华东理工大学学报（自然科学版）2026，Vol.52Issue(2)：225-232,8.DOI:10.14135/j.cnki.1006-3080.20250610001
石油类样品中全氟化合物分析方法的建立与应用
Development and Application of Analytical Methods for Perfluorinated Compounds in Petroleum-Based Samples
摘要
Abstract
Perfluorinated compounds(PFCs)are extensively utilised in the petroleum industry.As a class of emerging contaminants,PFCs have the potential to enter the product chain during the refining process,which may lead to environmental pollution and endanger human health.However,efficient and reliable methods for the pretreatment and detection of PFCs in petroleum-based samples are still lacking.Therefore,an analytical method was developed in this study,combining ionic liquid(IL)extraction,solid-phase extraction(SPE)purification,and liquid chromatography tandem high-resolution mass spectrometry detection.Orthogonal experimental design was used to optimise the key pretreatment conditions.The optimised procedure yielded the following results:The sample was extracted with 0.25 mL of 1-butyl-3-methylimidazolium hexafluorophosphate([Bmim][PF6]).The extract was then diluted to 250 mL,adjusted to pH 5,and purified using a weak anion exchange SPE cartridge.The purified samples were separated on a C18 column and ionised by electrospray ionisation(ESI)in negative ion mode.Analysis was subsequently performed using an Orbitrap mass spectrometer in parallel reaction monitoring(PRM)mode.The limit of detection was as low as 0.014 ng/mL,and the limit of quantitation reached 0.059 ng/mL.The analytical method was applied to determine PFCs in crude oil and FCC tail oil.The detected concentrations ranged from 0.88×10-9-1.47×10-9 and 10.79×10-9-17.18×10-9,respectively,with recoveries ranging from 58%to 112%.The results demonstrated that the analytical method established in this study can effectively mitigate the matrix effect of petroleum samples,enable efficient enrichment and determination of PFCs,and be generally applicable to petroleum samples with diverse physicochemical properties.关键词
全氟化合物/新污染物/石油/离子液体/正交试验Key words
perfluorinated compounds(PFCs)/emerging contaminants(ECs)/petroleum/ionic liquids(ILs)/orthogonal experimental design(OED)分类
化学化工引用本文复制引用
王黎民,龙姿,蔡婷,鞠峰,镇华君,修光利,唐智和..石油类样品中全氟化合物分析方法的建立与应用[J].华东理工大学学报（自然科学版）,2026,52(2):225-232,8.基金项目
中国石油天然气股份有限公司前瞻性基础性技术攻关项目(2023DJ6907) （2023DJ6907）
