家畜生态学报2026，Vol.47Issue(4)：10-17,8.DOI:10.3969/j.issn.1673-1182.2026.04.002
GWAS和mGWAS在畜禽育种方面的应用
The Application of GWAS and mGWAS in Livestock and Poultry Breeding
摘要
Abstract
Genome-wide association study(GWAS)and metabolome-wide association study(mGWAS)are crucial methods for dissecting the genetic basis of complex traits in animals and plants,and have dem-onstrated extensive application value in livestock and poultry breeding research in recent years.GWAS links single nucleotide polymorphisms(SNPs)across the entire genome with target traits,identifying key genes and loci that influence economic traits in livestock and poultry.mGWAS,on the other hand,uses metabolites as phenotypes to reveal the molecular regulatory mechanisms underlying trait formation from a metabolic perspective,compensating for the deficiencies of traditional GWAS in fine phenotypic character-ization.This article systematically reviews the research progress of GWAS and mGWAS in the genetic breeding of important livestock and poultry species such as cattle,sheep,pigs,and birds,including their application achievements in various aspects such as milk production performance,meat quality traits,feed efficiency,coat color,and reproductive performance.It also anticipates their development prospects in multi-omics integration and precision breeding,aiming to provide theoretical basis and methodological ref-erences for livestock and poultry genetic improvement.关键词
全基因组关联分析/代谢物全基因组关联分析/畜禽育种/候选基因Key words
GWAS/mGWAS/livestock and poultry breeding/candidate gene分类
农业科技引用本文复制引用
任静,高振东,常梦琳,马若珊,邓卫东,种玉晴,席冬梅..GWAS和mGWAS在畜禽育种方面的应用[J].家畜生态学报,2026,47(4):10-17,8.基金项目
贵州大学高原山地动物遗传育种与繁殖教育部重点实验室开放基金课题(黔教技[2022]424号) （黔教技[2022]424号）
云南农业大学科研启动费项目(KY2022-58) （KY2022-58）
