寄生虫与医学昆虫学报2026，Vol.33Issue(1)：75-80,6.DOI:10.3969/j.issn.1005-0507.2026.01.014
虫源性MicroRNA在棘球蚴及棘球蚴病中的研究进展
RESEARCH PROGRESS OF PARASITE-DERIVED MICRORNA IN ECHINOCOCCUS AND ECHINOCOCCOSIS
摘要
Abstract
Echinococcosis is categorized into alveolar echinococcosis and cystic echinococcosis,a potentially fatal zoonotic disease that seriously damages the host.MicroRNA is a type of endogenous small non-coding RNA that binds specifically to the target gene mRNA sequence to promote mRNA degradation,or combines with other non-coding RNA to regulate or inhibit translation.Echinococcus-derived microRNA participates in various biological processes in the Echinococcus lifecycle and in the interaction and pathogenesis between Echinococcus and host through extracellular vesicle transport.This article reviews the research progress of parasite-derived microRNA in regulating the growth and development of echinococcosis and cross-species regulation of hosts,providing a reference for diagnosing and treating echinococcosis.关键词
棘球蚴病/MicroRNA/跨物种调控Key words
Echinococcosis/MicroRNA/Cross-species regulation分类
医药卫生引用本文复制引用
张宏斌,杨宁,毕晓娟,林仁勇..虫源性MicroRNA在棘球蚴及棘球蚴病中的研究进展[J].寄生虫与医学昆虫学报,2026,33(1):75-80,6.基金项目
国家自然科学基金(No.82060371) （No.82060371）
新疆维吾尔自治区"天山英才"培养计划(No.2022TSYCLJ0032) （No.2022TSYCLJ0032）
新疆维吾尔自治区自然科学基金(No.2022D01D59) （No.2022D01D59）
新疆地区高发疾病研究教育部重点实验室开放课题青年项目(No.2023C06) （No.2023C06）
新疆维吾尔自治区研究生科研创新项目(No.XJ2024G144) （No.XJ2024G144）
