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饮酒状态对中重度创伤性脑损伤患者临床特征和预后的影响

张天鹏 吴鑫煦 胡方琪 朱家球 成丰宇 李明星 冯远卓 周辉 施辉

临床神经外科杂志2026,Vol.23Issue(2):207-212,6.
临床神经外科杂志2026,Vol.23Issue(2):207-212,6.DOI:10.3969/j.issn.1672-7770.2026.02.015

饮酒状态对中重度创伤性脑损伤患者临床特征和预后的影响

Effects of drunken status on clinical characteristics and outcomes in patients with moderate to severe traumatic brain injury

张天鹏 1吴鑫煦 1胡方琪 1朱家球 1成丰宇 2李明星 1冯远卓 2周辉 1施辉1

作者信息

  • 1. 222000 连云港,徐州医科大学附属连云港医院神经外科
  • 2. 南京医科大学连云港临床医学院神经外科
  • 折叠

摘要

Abstract

Objective To investigate the association between drunk at the time of injury and the clinical characteristics and prognosis of patients with moderate to severe traumatic brain injury(msTBI).Methods The clinical data of 282 patients with msTBI admitted to the Affiliated Lianyungang Hospital of Xuzhou Medical University from January 2020 to June 2024 were analyzed retrospectively,and they were categorized into alcohol and non-alcohol groups according to drunken at the time of injury.Univariable and multivariable Logistic regression analysis were performed to control for potential confounders and to evaluate the independent associations between drunken and key clinical outcomes.Results Multivariable Logistic regression analysis showed that drunken status was independently associated with a reduced risk of unfavorable short-term outcomes in patients with moderate to severe traumatic brain injury(OR=0.36,95%CI=0.16-0.78,P=0.009).Drunken status was also independently associated with shorter total hospital length of stay(OR=0.38,95%CI=0.18-0.79,P=0.009)and shorter ICU length of stay(OR=0.41,95%CI=0.21-0.83,P=0.013).No significant associations were observed between drunken status and total hospitalization costs or the incidence of postoperative pulmonary infection(all P>0.05).Conclusions Drunken status was associated with differences in clinical characteristics and was independently associated with a reduced risk of unfavorable short-term outcomes in patients with msTBI.

关键词

创伤性脑损伤/酒精/临床特征/结局

Key words

traumatic brain injury/alcohol/clinical characteristic/outcome

分类

医药卫生

引用本文复制引用

张天鹏,吴鑫煦,胡方琪,朱家球,成丰宇,李明星,冯远卓,周辉,施辉..饮酒状态对中重度创伤性脑损伤患者临床特征和预后的影响[J].临床神经外科杂志,2026,23(2):207-212,6.

基金项目

连云港市科学技术局基金资助项目(JCYJ2306) (JCYJ2306)

临床神经外科杂志

1672-7770

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