临床神经外科杂志2026,Vol.23Issue(2):207-212,6.DOI:10.3969/j.issn.1672-7770.2026.02.015
饮酒状态对中重度创伤性脑损伤患者临床特征和预后的影响
Effects of drunken status on clinical characteristics and outcomes in patients with moderate to severe traumatic brain injury
摘要
Abstract
Objective To investigate the association between drunk at the time of injury and the clinical characteristics and prognosis of patients with moderate to severe traumatic brain injury(msTBI).Methods The clinical data of 282 patients with msTBI admitted to the Affiliated Lianyungang Hospital of Xuzhou Medical University from January 2020 to June 2024 were analyzed retrospectively,and they were categorized into alcohol and non-alcohol groups according to drunken at the time of injury.Univariable and multivariable Logistic regression analysis were performed to control for potential confounders and to evaluate the independent associations between drunken and key clinical outcomes.Results Multivariable Logistic regression analysis showed that drunken status was independently associated with a reduced risk of unfavorable short-term outcomes in patients with moderate to severe traumatic brain injury(OR=0.36,95%CI=0.16-0.78,P=0.009).Drunken status was also independently associated with shorter total hospital length of stay(OR=0.38,95%CI=0.18-0.79,P=0.009)and shorter ICU length of stay(OR=0.41,95%CI=0.21-0.83,P=0.013).No significant associations were observed between drunken status and total hospitalization costs or the incidence of postoperative pulmonary infection(all P>0.05).Conclusions Drunken status was associated with differences in clinical characteristics and was independently associated with a reduced risk of unfavorable short-term outcomes in patients with msTBI.关键词
创伤性脑损伤/酒精/临床特征/结局Key words
traumatic brain injury/alcohol/clinical characteristic/outcome分类
医药卫生引用本文复制引用
张天鹏,吴鑫煦,胡方琪,朱家球,成丰宇,李明星,冯远卓,周辉,施辉..饮酒状态对中重度创伤性脑损伤患者临床特征和预后的影响[J].临床神经外科杂志,2026,23(2):207-212,6.基金项目
连云港市科学技术局基金资助项目(JCYJ2306) (JCYJ2306)