生态与农村环境学报2026，Vol.42Issue(4)：461-468,8.DOI:10.19741/j.issn.1673-4831.2025.0756
基于靶向和非靶向筛查技术的农药场地特征污染物筛选研究
Screening of Characteristic Pollutants in Pesticide Sites Based on Targeted and Non-targeted Screening Tech-niques
摘要
Abstract
Identifying characteristic pollutants at pesticide-contaminated sites is challenging due to the complex composi-tion and diversity of pesticide residues and their transformation products.To address this issue,this study proposes a novel screening framework that integrates targeted and non-targeted analytical approaches using ultra-high-performance liquid chromatography-triple quadrupole tandem mass spectrometry(UPLC-MS/MS)and ultra-high-performance liquid chroma-tography-quadrupole time-of-flight tandem mass spectrometry(UPLC-QTOF-MS).A comprehensive scoring system based on 12 evaluation indicators-including structural identification confidence,relative peak area,overall detection frequency,and metabolite identification etc.,was established to improve the accuracy and efficiency of characteristic pollutant identi-fication.A pesticide-contaminated site in Jiangsu Province was selected as a case study.Targeted analysis detected nine pesticides,while non-targeted analysis identified eleven pesticides and related metabolites.These include six fungicides(carbendazim,azoxystrobin,pyraclostrobin,thiophanate-methyl,tebuconazole,and difenoconazole),one metabolite(benzimidazole),three herbicides(atrazine,pretilachlor,and flumioxazin),and one insecticide(paclobutrazol).Based on the proposed framework,carbendazim,atrazine,and tebuconazole were identified as the characteristic pollutants at the study site.This approach provides a practical strategy for the systematic identification of characteristic pollutants at pesti-cide-contaminated sites.关键词
农药场地/高分辨质谱/靶向筛查/非靶向筛查/特征污染物Key words
pesticide site/high resolution mass spectrometry/targeted screening/non-targeted screening/characteristic contaminants分类
资源环境引用本文复制引用
曹莉,宋宁慧,葛峰,李菊颖,豆叶枝,乔禹欣,余佳,孔德洋,吴文铸,祝欣..基于靶向和非靶向筛查技术的农药场地特征污染物筛选研究[J].生态与农村环境学报,2026,42(4):461-468,8.基金项目
中央级公益性科研院所基本科研业务专项(GYZX230104) （GYZX230104）
生态环境部南京环境科学研究所"长三角生态环境保护一体化"研究院项目(ZX2022QT047) （ZX2022QT047）
