南京工业大学学报（自然科学版）2026，Vol.48Issue(1)：12-26,15.DOI:10.3969/j.issn.1671-7627.2026.01.002
基于柔性传感器的电子皮肤和经皮给药相结合的应用前景
Application prospects for integrating flexible sensor-based electronic skin with transdermal drug delivery
摘要
Abstract
This paper examines the development of electronic skin(e-skin)devices and transdermal drug delivery(TDD)systems.E-skin,made from flexible conductive polymers,can conform closely to human skin and has potential as a platform for TDD.Combining e-skin with TDD provides a new approach for intelligent and personalized healthcare.TDD delivers drugs directly through the skin,avoiding oral or injectable administration.It is painless,enables sustained release,and offers high efficiency.However,it is limited by the skin barrier and uncontrolled drug release.Integrating e-skin with flexible sensors enables real-time monitoring of physiological signals and precise control of drug release based on feedback.This approach overcomes the limitations of traditional TDD and enables smart,dynamic drug management.This paper reviews the current status of e-skin technology and its applications in TDD and skin disease management.Examples include flexible microneedle patches for treating diabetes,smart contact lenses for glucose monitoring,and electronic facial masks that enhance drug penetration.Technical challenges in combining flexible sensors with drug delivery systems are also discussed.In the future,integrating e-skin with AI and big data could further advance precision and remote healthcare,thus opening new directions for personalized therapy.关键词
电子皮肤/经皮给药/柔性传感器/微针给药技术/智能化给药Key words
electronic skin/transdermal drug delivery/flexible sensor/microneedle drug delivery/intelligent drug delivery分类
社会科学引用本文复制引用
李茂,徐淼,张晟,李安英,傅裕康,夏庆华,王朝,周瑜林,汪倩倩..基于柔性传感器的电子皮肤和经皮给药相结合的应用前景[J].南京工业大学学报（自然科学版）,2026,48(1):12-26,15.基金项目
2024年宁波市"科创甬江2035"关键技术突破计划(2024Z234、2024Z148) （2024Z234、2024Z148）
