南京工业大学学报（自然科学版）2026，Vol.48Issue(1)：81-88,8.DOI:10.3969/j.issn.1671-7627.2026.01.008
微流体纺丝改进氧化钛纳米晶须SERS性能的重复性
Reproducibility improvement of SERS performance in TiO2 nanowhiskers through microfluidic spinning
摘要
Abstract
The reproducibility of substrates for surface-enhanced Raman spectroscopy(SERS)is a key barrier to their applications.This study aims to improve the stability of SERS signals produced by TiO2 nanowhiskers and to increase their enhancement factor(EF).We used microfluidic spinning to generate spatially ordered arrays of TiO2 nanowhiskers and investigated how whisker mass concentration and heat-treatment temperature affect their morphology and SERS performance.The results show that microfluidic spinning successfully achieved the directional alignment of TiO2 nanowhiskers,with SEM images revealing a transition from disordered whiskers to uniform and ordered TiO2 whisker arrays,resulting in a significant enhancement in SERS performance.Using methylene blue(MB)as the probe molecule,the ordered substrate(S-TiO2)achieved a relative standard deviation(RSD)of 17.16％,and its EF increased from 7.5 × 105 to 1.4 × 106.Optimization indicates that a TiO2 nanowhisker concentration of 10 mg/mL and a heat-treatment temperature of 500 ℃ produce the highest structural order and the strongest SERS signals.These findings demonstrate that microfluidic spinning can effectively enhance the reproducibility of semiconductor-based SERS substrates by inducing ordered nanostructure alignment,providing a general and low-cost strategy for producing semiconductor-based SERS substrates.关键词
TiO2/纳米晶须/亚甲基蓝/表面增强拉曼/微流体纺丝Key words
TiO2/nanowhiskers/methylene blue/SERS/microfluidic spinning分类
化学化工引用本文复制引用
钱坤,刘畅..微流体纺丝改进氧化钛纳米晶须SERS性能的重复性[J].南京工业大学学报（自然科学版）,2026,48(1):81-88,8.基金项目
国家自然科学基金(21878143) （21878143）
